The Company is currently leveraging the pro-inflammatory mechanism of action of BXCL701 for treatment-Emergent
Neuroendocrine Prostate cancer and Pancreatic cancer.
adverse events were reported for 28.5% in these patients, though Dr.
At Week 96, 99.5% of women who received Biktarvy throughout the study duration and 98.5 % of women who switched to Biktarvy at Week 48 maintained virologic suppression (missing=excluded; M=E), with no development of treatment-emergent
adverse events were more frequent with ixekizumab.
The management of treatment-emergent
mania has not been well described and is generally similar to the management of acute manic episodes.
adverse effects were mild or moderate in intensity; no serious adverse events were reported.
In examining safety data from the pooled trials, Lydie Hazan, MD, of Axis Clinical Trials and her collaborators found that, for pediatric patients, most treatment-emergent
adverse events (AEs) were skin and subcutaneous tissue-related.
No patients in the fezolinetant group reported serious treatment-emergent
Safety and tolerability are being assessed by treatment-emergent
adverse event observations, vital sign assessments and laboratory tests, concluded the company.
The incidence of treatment-emergent
adverse events was comparable among both groups.
The major tolerability issue in the phase III trial was treatment-emergent
akathisia, which occurred in 37% of participants.