trazodone


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trazodone

 [tra´zo-dōn]
an antidepressant used orally as the hydrochloride salt to treat major depressive episodes with or without prominent anxiety

trazodone

(trā′zə-dōn′)
n.
A white odorless crystalline compound, C19H22ClN5O, used in its hydrochloride form as an antidepressant.

trazodone

Desyrel® Pharmacology An SSRI-antidepressant that blocks postsynaptic serotonin-5HT and alpha-adrenergic receptors; it is therapeutically similar to desimipramine, et al Contraindications Pregnancy, arrhythmias, post-MI Adverse effects Sedation, postural hypotension, ventricular arrhythmias. See Selective serotonin reuptake inhibitor.

trazodone

An antidepressant drug. A brand name is Molipaxin.
References in periodicals archive ?
Table 1 Medications associated with serotonin syndrome Class Medication(s) Antidepressants Selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, tricyclic antidepressants Monoamine oxidase inhibitors Trazodone Mirtazapine Triptans Almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan Anxiolytics Buspirone Antiemetics Ondansetron, granisetron, metoclopramide Herbal supplements St.
Procedures: During the first of 3 experiments, birds received orally administered trazodone at doses ranging from 3 to 30 mg/kg to determine the dose for subsequent experiments.
Klein and her colleagues noted that 871 unique children were prescribed 5,190 30-day-supply prescriptions for trazodone, including 23 children under age 5.
Regarding the persistence of priapism following discontinuation of the original inciting agent, trazodone, it has been hypothesized that this may be due to irreversible fibrotic changes in penile smooth muscle which persist following the withdrawal of trazodone (3).
Professor Giovanna Mallucci, who led the team from the Medical Research Council's Toxicology Unit in Leicester and Cambridge University, said: "We know that trazodone is safe to use in humans, so a clinical trial is now possible to test whether the protective effects of the drug we see on brain cells in mice with neurodegeneration also apply to people in the early stages of Alzheimer's and other dementias.
Medications not recommended for treating either sleep initiation or sleep maintenance insomnia include: diphenhydramine, melatonin, tiagabine, trazodone, tryptophan, and valerian.
In the absence of any emotional and behavioral problem, he has been diagnosed with primary insomnia, and he has been prescribed with trazodone 100 mg.
Patient and her familywere informed of the possible alternatives for managing the relapse of symptomatology including the further rising of paroxetine or mirtazapine dosage; augmentation strategies (including thyroid hormones and mood stabilizers or antipsychotics in lower doses); the addition of a third antidepressant that has sedative properties and relatively well tolerable side-effect profile, such as trazodone; or alternatively ECT.
Targeting dopaminergic pathways to increase desire, an extended-release daily oral combination of trazodone and bupropion, to be marketed as Lorexys, is about to begin phase III clinical trials.
It may also interact negatively with certain prescription medications and over-the-counter drugs, including: NSAIDs (such as aspirin and ibuprofen); warfarin (Coumadin); ticlopidine (Ticlid); clopidogrel (Plavix); and dipyridamole (Persantine) alprazolam (Xanax), haloperidol (Haldol), Trazodone (Desyrel), omeprazole (Prilosec), and nifedipine (Procardia).
Low-dose trazodone 25-50mg works well for many PWD with fewer side effects than other medications.