travoprost


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travoprost

 [trav´o-prost]
a synthetic prostaglandin analogue used in the treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension; administered topically to the conjunctiva.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

travoprost

A PROSTAGLANDIN analogue drug used in eye drops to control intraocular pressure in open angle GLAUCOMA. A brand name is Travatan.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

prostaglandin analogues 

Drugs used in the treatment of open-angle glaucoma or ocular hypertension. At specific dosages they lower the intraocular pressure (IOP), supposedly by increasing the outflow of aqueous humour via the uveoscleral pathway. Common agents include latanoprost, travoprost, bimatoprost (a synthetic prostamide structurally related to prostaglandin) and unoprostone isopropyl. Bimatoprost reduces IOP by increasing the uveoscleral outflow as well as the trabecular outflow.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
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References in periodicals archive ?
OTX-TP (intracanalicular travoprost insert) is an intracanalicular insert in Phase 3 clinical development for the reduction of intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension.
Ocular Therapeutix to Present at the 2019 Wells Fargo Healthcare Conference
The company's earlier stage assets include OTX-TIC, an extended-delivery intracameral travoprost implant for the reduction of intraocular pressure in patients with glaucoma and ocular hypertension, as well as sustained release intravitreal implants for the treatment of retinal diseases.
Ocular Therapeutix Assigned Permanent and Specific J-Code (J1096) for Dextenza 0.4mg by the Centers for Medicare and Medicaid Services
Ocular Therapeutix announced topline results from the first pivotal Phase 3 clinical trial of OTX-TP, an intracanalicular insert that delivers a preservative-free formulation of the drug travoprost for the reduction of intraocular pressure in patients with primary open-angle glaucoma or ocular hypertension.
Ocular Therapeutix says OTX-TP failed to meet primary endpoint in Phase 3 trial
Sustained effect of travoprost on diurnal and nocturnal intraocular pressure.
Evaluation of the Effect of Body Position on Intraocular Pressure Measured with Rebound Tonometer
As an example, both latanoprost and travoprost are aimed at glaucoma treatment, but the tolerability of either drug among patients varies.
PROJECT PORTFOLIO OPTIMIZATION AS A PART OF STRATEGY IMPLEMENTATION PROCESS IN SMALL AND MEDIUM-SIZED ENTERPRISES: A METHODOLOGY OF THE SELECTION OF PROJECTS WITH THE AIM TO BALANCE STRATEGY, RISK AND PERFORMANCE
In this study, LayerBio's proprietary intracameral extended-release formulation of the glaucoma drug travoprost is shown to lower intraocular pressure to therapeutic levels for longer than six months.
LayerBio to Present Preclinical Results for Extended Release Glaucoma Formulation at ARVO
IOP of the OD remained consistently above 50 mmHg with medications provided (i.e., travoprost, timolol, brinzolamide, brimonidine tartrate, and mannitol 20%).
One Eye Suffering from Ocular Decompression Retinopathy after Trabeculectomy in a Patient with Juvenile Open-Angle Glaucoma
The currently prescribed PGAs in our region are bimatoprost 0.01% (with BAK 0.02%), latanoprost 0.005% (with BAK 0.02%), travoprost 0.004% (with 0.001% polyquad), and tafluprost 0.0015% (preservative-free).
Comparison of Efficacy and Ocular Surface Disease Index Score between Bimatoprost, Latanoprost, Travoprost, and Tafluprost in Glaucoma Patients
Later in 2014, Kucukevcilioglu and coworkers (2) described deepening of the upper eyelid sulcus in other PA, such as Latanoprost and Travoprost. Other studies describe different side effects of PA, such as conjunctival hyperemia, elongation and darkening of eyelashes, induced iris darkening, and periocular skin pigmentation (3-5).
Periorbital Changes associated with Topical Prostaglandins Analogues in a Hispanic Population
Prostaglandin analogues and mouse intraocular pressure: effects of tafluprost, latanoprost, travoprost, and unoprostone, considering 24-hour variation.
Effects of dorzolamide/timolol and tafluprost on intraocular pressure and pupil diameter in healthy dogs/Efeitos da dorzolamida/Timolol e da tafluprosta sobre a pressao intraocular e o diametro pupilar em caes saudaveis
and prostaglandin analogs such as latanoprost, travoprost are playing an increasingly important role in the first-line therapy of glaucoma [6,8] The ocular hypotensive effect of once daily 0.5% timolol ranges from 17% to 28% which overlaps with that of twice daily timolol.
Evaluation of efficacy of the fixed vs unfixed combination of latanoprost and timolol in patients of open-angle glaucoma and ocular hypertension insufficiently controlled on timolol and latanoprost monotherapy

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