Transtubular potassium gradient | definition of transtubular potassium gradient by Medical dictionary
transtubular potassium gradient
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transtubular potassium gradient (trans″too′byŭ-lăr′) [ trans- + tubular],
A measurement of how avidly the kidneys retain potassium. The TTKG is used clinically to determine the cause of high serum potassium levels. It is represented mathematically as the urinary potassium concentration/plasma potassium concentration, all divided by the osmolality of urine/the plasma osmolality.
References in periodicals archive
Another index that has been proposed for the evaluation of urine-potassium loss is the transtubular potassium gradient
Her renin level was <4.5 mIU/l (low), aldosterone was 2 234 pmol/l (high) and her transtubular potassium gradient
was 17 (high).