transpulmonary pressure


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Related to transpulmonary pressure: alveolar pressure, intrapleural pressure

trans·pul·mo·nar·y pres·sure

the difference between the pressure of the respired gas at the mouth and the pleural pressure around the lungs, measured when the airway is open; thus, it includes not only the transmural pressure of the lung but also any drop in pressure along the tracheobronchial tree during flow.
Farlex Partner Medical Dictionary © Farlex 2012

transpulmonary pressure

Physiology The difference between airway pressure and pleural pressure–PAW—PPL, a clinically important respiratory measure in ICU Pts; it is also derived by multiplying the airway pressure by the ratio of lung parenchyma elastance and total lung elastance; for a given PAW, rise of the PPL has effects on hemodynamics, lung distention and recruitment, and interstitial lung fluid–pulmonary edema
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

trans·pul·mo·nar·y pres·sure

(trans-pul'mŏ-nar-ē presh'ŭr)
The pressure difference across the lungs; the difference between the pressure at the airway opening and the pressure on the visceral pleural surface (i.e., pressure at the airway opening - pleural pressure).
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Physiological correlation of airway pressure and transpulmonary pressure stress index on respiratory mechanics in acute respiratory failure.
The aim is to homogenize transpulmonary pressure and reduce intrapulmonary shunt.
The IOS approach in neonates has not been validated against an accepted "gold standard" technique of respiratory function measurement (i.e., the use of an esophageal balloon to determine transpulmonary pressures to separate the chest wall and lung components of the resistance spectrum).
The importance of intrapleural pressure to the determination of transpulmonary pressure and therefore actual lung stretch has been recently emphasized in work by Talmor and colleagues (NEJM 2008), who set PEEP in ARDS effectively using transpulmonary pressure, determined as the difference between airway and esophageal balloon ("pleural") pressures.
Generation of transpulmonary pressure sufficient to exceed airway opening pressure, elimination of lung compression by the heart, non-gravitational distribution of perfusion and attenuation of lung injury have been proposed as mechanisms for the effect of prone positioning (8-12).
Applied Research of New Lung Ventilation Strategies Guided by Transpulmonary Pressure in Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome.
If the patient actively contributes to lung expansion--and this is encouraged in many excellent centers so as to improve the distribution of ventilation and to avoid muscular atrophy--any residual inspiratory tone at end inspiration adds to the transpulmonary pressure and to lung tissue stress.
Transpulmonary pressure gradients and alveolar inflation become more homogeneous (4) and there is less extensive dependent atelectasis (3).