transporter associated with antigen processing

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A gene on chromosome 6p21.3 that encodes a member of the MDR/TAP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which plays a role in multidrug resistance. TAP1 pumps degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment.

Molecular pathology
TAP1 mutations have been tentatively linked to ankylosing spondylitis, type 1 diabetes and coeliac disease.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

transporter associated with antigen processing



An intracellular protein that carries antigens to the endoplasmic reticulum of cells, where the antigens may be transformed for presentation.
Medical Dictionary, © 2009 Farlex and Partners
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