The product was developed by Corium, a specialty pharma company focused on the development and manufacture of transdermal and transmucosal delivery
A similar strategy may enable the technology to be used successfully in transmucosal delivery
. Transport through mucosal membranes presents similar advantages to transdermal delivery but requires different features: larger vehicles with a high molecular weight and high charge to resist being washed away and be more effectively retained in the mucosa.
Pokharkar, "Chitosan reduced gold nanoparticles as novel carriers for transmucosal delivery
of insulin," Pharmaceutical Research, vol.
is a specialty pharmaceutical company focused on the development of a portfolio of wound management and oral care products to provide patients and consumers improved clinical outcomes through controlled delivery utilising its innovative NanoflexAggregate technology and OraDisc transmucosal delivery
* A transmucosal delivery
patch as described in US patent publication 2009/0304776 Al.
Its family of medical marijuana products will begin with a metered-dose transmucosal delivery
system, a cannabis infused beverage line and transdermal patches.
Transdermal, nasal, inhaled-pulmonary and oral transmucosal delivery
formulations enable drug uptake directly into the blood, thereby eliminating first-pass metabolism.
 Kundu, J., Patra, C., Kundu, S.C., 2008, "Design, fabrication, and characterization of silk fibroin-HPMC-PEG blended films as vehicle for transmucosal delivery
Auxilium's transmucosal film product candidate for the treatment of overactive bladder (AA4010) and its fentanyl pain product using its transmucosal delivery
system are in phase I of development.
After an overview of the fundamentals, contributions address such topics as preclinical assessment of oral mucosal systems; modulation of oral transmucosal permeability; oral transmucosal delivery
of protein and peptide therapeutics; sublingual transmucosal delivery
of organic nitrates for the treatment of angina pectoris; oral transmucosal delivery
of melatonin; oral transmucosal powder injection; drug delivery systems for the treatment of periodontal and dental diseases; oral transmucosal systems for local anesthetics; quick-dispersing oral drug delivery systems; and scientific and regulatory considerations of quick-dissolving oral dosage forms.
Humphreys presented: "Transmucosal Delivery
of Therapeutics by RapidMist(R) Technology and TH-1 T-helper cell Ii-Key/MHC Class II Peptide Vaccines against Cancer and HIV."
The agreement fits into our sublicensing strategy and makes the BEMA technology available to other pharmaceutical companies in need of a robust transmucosal delivery