transmethylation


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transmethylation

 [trans″meth-ĭ-la´shun]
the transfer of a methyl group (CH3=) from the molecules of one compound to those of another.

trans·meth·y·la·tion

(trans'meth-i-lā'shŭn),
Transfer of a methyl group from one compound to another; for example, l-homocysteine is converted to l-methionine by the transfer to the latter of a methyl group. See: methionine synthase.

transmethylation

/trans·meth·y·la·tion/ (trans″meth-ĭ-la´shun) the transfer of a methyl group (CH3—) from one compound to another.

transmethylation

[-meth′ilā′shən]
the transfer of a methyl group from one compound to another.

trans·meth·y·la·tion

(trans'meth-i-lā'shŭn)
Transfer of a methyl group from one compound to another.

transmethylation

the transfer of a methyl group (CH3) from the molecules of one compound to those of another.
References in periodicals archive ?
Each lipid extract underwent basic transmethylation in duplicate using potassium hydroxide in MeOH, following Ichihara's procedure (Ichihara et al.
Hcy metabolized through the transsulfuration and transmethylation pathways, where folate, vitamin B-12 and vitamin B-6 are involved as a substrate or cofactor.
Thus, an acid-catalysed treatment of SPE converts both BFA and FFA into FAME, allowing the measurement of all individual fatty acids regardless of their initial form (free or bound); following alkali-catalysed transmethylation, only the bound fatty acids are converted into FAME.
Addition of homocystine to the diet probably increases tHcy directly and leads to a product excess in methionine metabolism, inhibiting transmethylation and thereby the utilization of methionine.
TMG upregulates a host of enzymes and recycles homocysteine to methionine and enhances transmethylation processes.
It is noteworthy that the formation of creatinine from methylation of guanidinoacetate accounts for approximately 75% of all folate-dependent transmethylation reactions (Barr et al.
Effects of the disruption of transmethylation in the central nervous system: an animal model.
Methionine-adenosyl-transferases are enzymes involved in transmethylation reaction.
Currently, several pharmacological mechanisms of methotrexate action have been suggested, including inhibition of purine and pyrimidine synthesis, suppression of transmethylation reactions with accumulation of polyamines, reduction of antigen-dependent T-cell proliferation, and promotion of adenosine release with adenosine-mediated suppression of inflammation.
The importance of the transmethylation pathway in the central nervous system has been outlined (5, 6).