translocation Down syndrome

translocation Down syndrome

n.
A condition in which, as a result of translocation of a large segment of chromosome 21 to another chromosome, an individual has virtually the genetic equivalent of three chromosomes 21 and thus has the phenotype of Down syndrome but with the normal number of chromosomes.
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References in periodicals archive ?
C3-15) Most children with translocation Down syndrome are born to mothers under the age of 21-25 year; therefore not depend on maternal age.