TOM complex of protein translocators

(redirected from translocase of outer mitochondrial membrane)

TOM complex of protein translocators

(tom kom'pleks prō'tēn trans'lō-kā-tŏrz),
multisubunit protein complex located in the outer membrane of mitochondria; responsible for transport of mitochondrial proteins, encoded in the nucleus and synthesized in the cytosol, into the intermembrane space and inserting the proper proteins into the outer mitochondrial membrane.
See also: OXA complex of protein translocators.
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The trial will use a genetic-based biomarker risk assignment algorithm comprised of apolipoprotein E (APOE) and Translocase of Outer Mitochondrial Membrane (TOMM40) genotypes and age, which is being studied to determine the risk of individuals developing mild cognitive impairment (MCI) due to Alzheimer's disease (AD) within a five year period.