transitional cell


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Related to transitional cell: transitional epithelium

tran·si·tion·al cell

any cell thought to represent a phase of development from one form to another.

T cell

Cardiology
A specialised myocyte found in clusters in the sinus node, which is intermediate in size, structure, and organisation between P cells and normal atrial myocytes, and connect swith either of these cells; perinodal T cells surround the sinus tract and are thought to “bundle” impulses leaving the sinus node and to filter premature ectopic atrial impulses.

Immunology
A thymus-derived white cell responsible for cell-mediated immunity and immunoregulation which is the most complex cell of the immune system, given:
(1) The diversity of T-cell types, including T cells with activator, cytotoxic, delayed hypersensitivity and suppressor activities;
(2) The wide range of cytokines, growth factors and immune modulators produced by activated T cells;
(3) The complexity of T-cell interaction with exogenous and endogenous antigens (e.g., mediation of delayed hypersensitivity, graft-versus-host disease);
(4) The complexity of T-cell maturation in the thymus.

50 to 70% of circulating WBCs are granulocytes (neutrophils); the rest are lymphocytes, of which T cells (defined as having “pan T cell” markers), CD2 and CD7 and other T-cell markers (e.g., CD1, CD3, and CD5) comprise 70 to 85%; B cells comprise 15 to 30%.

transitional cell

The stretchable epithelial cells that compose the transitional epithelium (uroepithelium), which lines most of the urinary tract. Transitional cells are strongly interconnected. They are cuboidal when not under pressure, and they become flattened and squamous when stretched. Transitional epithelia are 4-6 cells thick, and the top transitional cells -- those on the lumenal surface -- fuse to become larger and polyploid.
See also: cell

transitional cell

cells which make up an epithelium, e.g. in the urinary bladder, consisting of several layers of soft cuboidal cells which flatten out when stretched.

transitional cell tumors
1. adenomas, papillomas and carcinomas of transitional epithelium in the urinary tract; they are the most common tumors of the urinary bladder in dogs.
2. carcinoma of the upper respiratory tract.
References in periodicals archive ?
Differential C-erb B2 and VEGF expression following BCG immunotherapy in superficial papillary transitional cell carcinoma of the bladder.
Both mitomycin C and Bacillus Calmette-Guerin have been used in children, however, efficacy of intravesical treatments has not been defined due to the rarity of transitional cell carcinoma of the bladder in children (7).
Significance of matrix metalloproteinase and tissue inhibitors of metalloproteinase expression in the recurrence of superficial transitional cell carcinoma of the bladder.
A phase II study of gemcitabine in patients with transitional cell carcinoma of the urinary tract previously treatedwith platinum.
The report provides a snapshot of the global therapeutic landscape of Transitional Cell Cancer (Urothelial Cell Cancer)
The study compared results of urine cytology and the test for urinary s-Fas level in healthy controls and 117 patients with transitional cell carcinoma (TCC), the most common form of bladder cancer among diabetics.
Key Words: Transitional cell carcinoma, hematuria, pediatrics, children, urothelial bladder tumor.
iii) Four tumours exhibited focally recognizable patterns of transitional cell (urothelial) carcinoma in the available material.
3) Schistosoma hematobium is thought to be pathogenetically related to squamous cell carcinoma (SCC) as well as transitional cell carcinoma of the bladder.
Subsequent histopathological examination confirmed a transitional cell carcinoma (TCC).
This report provides information on the therapeutic development for Transitional Cell Carcinoma (Urothelial Cell Carcinoma), complete with latest updates, and special features on late-stage and discontinued projects.
Upper urinary tract transitional cell cancer after radical cystectomy for bladder cancer.

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