transitional cell


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Related to transitional cell: transitional epithelium

tran·si·tion·al cell

any cell thought to represent a phase of development from one form to another.

T cell

Cardiology
A specialised myocyte found in clusters in the sinus node, which is intermediate in size, structure, and organisation between P cells and normal atrial myocytes, and connect swith either of these cells; perinodal T cells surround the sinus tract and are thought to “bundle” impulses leaving the sinus node and to filter premature ectopic atrial impulses.

Immunology
A thymus-derived white cell responsible for cell-mediated immunity and immunoregulation which is the most complex cell of the immune system, given:
(1) The diversity of T-cell types, including T cells with activator, cytotoxic, delayed hypersensitivity and suppressor activities;
(2) The wide range of cytokines, growth factors and immune modulators produced by activated T cells;
(3) The complexity of T-cell interaction with exogenous and endogenous antigens (e.g., mediation of delayed hypersensitivity, graft-versus-host disease);
(4) The complexity of T-cell maturation in the thymus.

50 to 70% of circulating WBCs are granulocytes (neutrophils); the rest are lymphocytes, of which T cells (defined as having “pan T cell” markers), CD2 and CD7 and other T-cell markers (e.g., CD1, CD3, and CD5) comprise 70 to 85%; B cells comprise 15 to 30%.

transitional cell

The stretchable epithelial cells that compose the transitional epithelium (uroepithelium), which lines most of the urinary tract. Transitional cells are strongly interconnected. They are cuboidal when not under pressure, and they become flattened and squamous when stretched. Transitional epithelia are 4-6 cells thick, and the top transitional cells -- those on the lumenal surface -- fuse to become larger and polyploid.
See also: cell

transitional cell

cells which make up an epithelium, e.g. in the urinary bladder, consisting of several layers of soft cuboidal cells which flatten out when stretched.

transitional cell tumors
1. adenomas, papillomas and carcinomas of transitional epithelium in the urinary tract; they are the most common tumors of the urinary bladder in dogs.
2. carcinoma of the upper respiratory tract.
References in periodicals archive ?
Nomograms including nuclear matrix protein 22 for prediction of disease recurrence and progression in patients with Ta, T1 or CIS transitional cell carcinoma of the bladder.
A rare cause of scrotal swelling: transitional cell carcinoma of the bladder presenting as a testicular metastasis.
We report on a case of advanced proximal urethral carcinoma treated with surgical resection; the patient was initially diagnosed with a transitional cell type during clinical staging, but after surgical resection, the tumour was revealed as an adenocarcinoma.
If the cells in the biopsy specimen represented transitional cell carcinoma, one would have expected cytokeratin stains to yield a positive reaction.
Renal cell cancer and concomitant transitional cell cancer of the renal pelvis and ureter in the same kidney - report of 4 cases and review of the literature.
The scope of this grant includes further examination of the blood stem cell to liver cell findings including the identification of a transitional cell capable of making hepatocytes.
NASDAQ: ALTH) today announced the initiation of patient enrollment in a Phase 2, open-label, single-arm, multi-center study of PDX (pralatrexate) in patients with advanced or metastatic relapsed transitional cell carcinoma (TCC) of the urinary bladder.
Upper urinary tract transitional cell carcinomas (TCC) are considered a relatively rare tumour type, and no internationally validated guidelines have been established for their treatment.
Approximately 90 percent of renal cancers are transitional cell carcinomas (TCC), a common type of cancer that originates from transitional epithelial cells lining the urinary tract and affects a significant portion of the U.
Transitional cell carcinoma of the bladder in patients with renal pelvic and ureteral cancer.

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