transition mutation


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Related to transition mutation: spontaneous mutation, transversion mutation

tran·si·tion mu·ta·tion

a point mutation involving substitution of one base-pair for another, that is, replacement of one purine for another and of one pyrimidine for another pyrimidine without change in the purine-pyrimidine orientation.

tran·si·tion mu·ta·tion

(tran-zish'ŭn myū-tā'shŭn)
A point mutation involving substitution of one base pair for another, i.e., replacement of one purine for another and of one pyrimidine for another pyrimidine without change in the purine-pyrimidine orientation.
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References in periodicals archive ?
If the simulations and numerical approximation reflect the actual situation, this means that there may be a great difference, approximately 150-fold, between the highest transition mutation rate and the transversion rate.
This study shows that using the Salmonella Mutagenicity Assay that idarubicin, like daunomycin, can induce frameshift (TA98; 16.1 fold), GC to AT (TA7004; 8.7 fold), and AT to GC base-substitution transition mutations (TA7001; 2.8 fold).
This study shows that in using the Salmonella Mutagenicity Assay that adriamycin can induce frameshift (TA98; 15.4-fold) and GC to AT transition mutations (TA 7004; 7.8-fold).

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