transient aplastic crisis


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transient aplastic crisis (TAC),

temporary suppression of erythropoiesis, due usually to viral infection (e.g., Parvovirus B-19); may be particularly severe in people with hemolytic anemias (e.g., sickle cell disease, thalassemia, hereditary spherocytosis).

transient aplastic crisis

Abbreviation: TAC
A serious complication of infection with human parvovirus B-19 infection in patients with chronic hemolytic anemia such as sickle cell disease. This virus causes erythema infectiosum.
See: erythema infectiosum
See also: crisis
References in periodicals archive ?
Transient aplastic crisis occurs in the case of underlying chronic hemolytic anemia conditions, and chronic PRC anemia is presented by persistent infection in immunocompromised individuals.

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