transient acantholytic dermatosis

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tran·sient a·can·tho·lyt·ic der·ma·to·sis

a pruritic papular eruption, with histologic suprabasal acantholysis, of the chest, with scattered lesions of the back and lateral aspects of the extremities, lasting from a few weeks to several months; seen predominantly in males over 40.
Synonym(s): Grover disease

tran·si·ent a·can·tho·lyt·ic der·ma·to·sis

(tran'sē-ĕnt a-kan'thŏ-lit'ik dĕr'mă-tō'sis)
A pruritic papular eruption of the chest, with scattered lesions of the back and lateral aspects of the limbs, lasting from weeks to months; seen predominantly in men older than 40 years of age.
Synonym(s): Grover disease.


Ralph W., U.S. dermatologist, 1920–.
Grover disease - a pruritic papular eruption. Synonym(s): transient acantholytic dermatosis
References in periodicals archive ?
According to a review of more than 150 elderly patients in the outpatient setting who presented with a chief complaint of persistent pruritus, the five most common diagnoses were atopiclike dermatosis, lichen simplex chronicus/prurigo nodularis, subacute prurigo, transient acantholytic dermatosis, and neuropathic disease.
Transient acantholytic dermatosis is a self-limited, primary, nonfamilial, non-immune-mediated acantholytic skin disorder that manifests as pruritic, discrete, edematous papules and/or a vesiculopapular rash and is more commonly referred to as Grover disease, after Dr Ralph Grover, who first reported the condition in 1970.
As mentioned previously, although the alternative term transient acantholytic dermatosis is synonymous with Grover disease, the duration of disease may actually extend for many months, and reports of chronic relapsing disease are not an uncommon occurrence.
The association of transient acantholytic dermatosis with other skin diseases.
Incidence of transient acantholytic dermatosis (Grover's disease) in a hospital setting.
Transient acantholytic dermatosis induced by recombinant human interleukin 4.
Transient acantholytic dermatosis (Grover's disease) in a patient with progressive systemic sclerosis treated with D-penicillamine.