There are a number of viral vector systems other than AAV, such as adenoviral-based vectors and lentivirus-based systems, each of which has individual strengths and weaknesses with regard to possible transgene
size, ease and safety of use, cellular tropism, and other factors.
This collaboration will co-develop next generation oncolytic virus (OV) candidates encoding an anti-CTLA-4 antibody sequence, potentially with additional transgenes
, capable of treating multiple solid tumours.
Eric Quemeneur, PhD, Executive VP and VP Research & Development of Transgene
, said: We are delighted to collaborate with Randox.
may receive more than 30 million Euro for this contract, with an initial duration of three years.
To construct the cumate-inducible transgene
expression vector, the green fluorescent protein (GFP) or MyoD gene was inserted into the piggyBac cumate switch inducible vector (System Biosciences, Palo Alto, CA, USA) after NheI/NotI digestion and ligation.
These samples were preceded for any transgene
presence detection through PCR and biochemical tests.
is a publicly traded French biopharmaceutical company focused on discovering and developing targeted immunotherapies for the treatment of cancer and infectious diseases.
The report reviews current pipeline of Transgene
SA's human therapeutic division and enlists all their major and minor projects
To improve the efficiency of selection of transgenics, genetic markers are co-injected with the transgene
to monitor for transformed zygotes.
The report provides brief overview of Transgene
Biotek Limited including business description, key information and facts, and its locations and subsidiaries
, which is unprofitable and hopes to have its first product on the market in 2015, wants to expand in the field to diversify from the development of therapeutic vaccines, its main business, Archinard said.