The Haemoglobin transfusion trigger
was 7-13 g/dl for the majority of scenarios.
It starts with TRICC trial giving a transfusion trigger
of 7.0 g/dl hemoglobin in non-cardiac and 10 g/dl in cardiac patients.
The 10-30 rule for transfusion trigger
was questioned by the 1999 study of Hebert et al.
Pawlik, "Identifying variations in blood use based on hemoglobin transfusion trigger
and target among hepatopancreaticobiliary surgeons," Journal of the American College of Surgeons, vol.
The publication of the TRICC (Transfusion Requirements in Critical Care) trial in 1999 showed that a restrictive approach to the use of red cell concentrates (RCCs) with a low haemoglobin (Hb) trigger of <8 g/dL had no harmful clinical effects and clinical outcomes were similar to those in patients treated with a more liberal transfusion regimen with the transfusion trigger
set at 10 g/dL.
Other studies  recommend transfusion trigger
for the restoration of the lost circulatory volume with RES.
Methods: From June 2013 to June 2014, patients were randomly divided into the experimental group (Peri-operative Transfusion Trigger
Score of Emergency [POTTS-E] group) and the control group (control group).
Ward personnel were informed about transfusion strategy assignment to ensure compliance with the protocol with the aim to treat transfusion trigger
deviations as protocol violations.
LBA-6 Transfusion trigger
trial for functional outcomes in cardiovascular patients undergoing surgical hip fracture repair (FOCUS): The principle results.
All together, there were 1,404 procedures represented resulting in a mortality rate due to anemia of between 0.5 to 1.5%.10 More often, a hospital-wide transfusion trigger
policy is in place that may support transfusions at very conservative hemoglobin concentrations.
In stable HIV-infected anaemic children, it is reasonable to consider a Hb <6 g/dl as the transfusion trigger
. (40,41) A threshold Hb of 7-8 g/dl is recommended in haemodynamically stable, critically ill patients (e.g.
Re-evalutaing the transfusion trigger
: how low is safe?