transforming growth factor beta


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trans·form·ing growth fac·tor β (TGFβ),

a regulatory cytokine that has multifunctional properties that can enhance or inhibit many cellular functions, including interfering with the production of other cytokines and enhancing collagen deposition. It exists in multiple subtypes and is produced by platelets and macrophages but can be made by many other cell types.
References in periodicals archive ?
The funding will be used to research the role and therapeutic potential of proteins involved in regulating localised release of transforming growth factor beta.
The authors have developed a novel technique for rabbit ear keloid model creation using Transforming Growth Factor Beta 1 injection, a pro-fibrotic cytokine, followed by composite punch excision.
Transforming growth factor beta modulates C3 and factor B biosynthesis and complement receptor 3 expression in cultured human monocytes.
Recently a prototype rabbit ear keloid model has been produced by the authors by giving Transforming Growth Factor Beta 1 injection, and then skin punch excision on rabbit ear.
MicroRNA-30 protects against carbon tetrachloride-induced liver fibrosis by attenuating transforming growth factor beta signaling in hepatic stellate cells.
Among the factors secreted by the oocyte, we highlight members of the transforming growth factor beta (TGF-[beta]) superfamily and, among these, the growth and differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15), which are expressed in all stages of follicular development in the bovine species and are involved in controlling the proliferation and steroidogenesis of granulosa cells (Juengel and McNatty, 2005).
He found that Nanog opens two key cellular pathways: Rho-associated protein kinase (ROCK) and Transforming growth factor beta (TGF-β).
It contains cytokines such as IL-1, -4, -6, and growth factors such as Transforming Growth Factor beta 1 (TGF-a1), Platelet Derived Growth Factor (PDGF), and Vascular Endothelial Growth Factor (VEGF).
AMSCs secrete higher levels of certain growth factors, including transforming growth factor beta (TGF-[I.
Bone contains a cocktail of growth factors including transforming growth factor beta (TGFP platelet derived growth factor (PDGF), bone morphogenetic proteins (BMPs), insulin-like growth factors I and II (IGF-I and IGF-II) and fibroblast growth factors (FGFs).

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