transforming growth factor beta


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trans·form·ing growth fac·tor β (TGFβ),

a regulatory cytokine that has multifunctional properties that can enhance or inhibit many cellular functions, including interfering with the production of other cytokines and enhancing collagen deposition. It exists in multiple subtypes and is produced by platelets and macrophages but can be made by many other cell types.

transforming growth factor beta (TGF-β),

n a substance that is produced by bone cells and platelets to promote bone regeneration and wound healing.
References in periodicals archive ?
A gene analysis of this group of people found that the higher the levels of IRF-5, the lower the levels of another protein produced by macrophages, transforming growth factor beta (TGFbeta).
Connective tissue growth factor (CTGF) is a member of a family of regulatory proteins, which along with transforming growth factor beta (TGF-[beta]), plays a central role in Type I collagen and extracellular matrix (ECM) production [1].
The cells in Lucanix have been modified to block production of transforming growth factor beta (TGF-B), which is one of the primary methods cancers use to hide from the immune system.
Now, a new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) reveals how antipsychotic drugs interfere with normal metabolism by activating a protein called SMAD3, an important part of the transforming growth factor beta (TGFbeta) pathway.
Some rabbits in the study received a bioscaffold infused with a collagen gel loaded with the protein, called transforming growth factor beta 3 (TGFB3), while other rabbits received bioscaffolds with TGFB3.
A team from Cancer Research and Breast Cancer Campaign examined a chemical in the body called transforming growth factor beta (TGF) and what it did to breast cancer cells.
Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene.
Other topics described include cellcycle arrest by dietary chemopreventive agents, insulin-like growth factor regulation of cell proliferation, trisomy of human chromosome 21 and cell cycle control, and transforming growth factor beta and cell cycle regulation.
Tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta 1 (TGF beta 1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts.
Transforming growth factor beta (TGF[beta]) is still another potent regulator of cellular activity that may regulate cardiac morphogenesis (Ross et al.

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