transforming growth factor


Also found in: Dictionary, Thesaurus, Legal, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to transforming growth factor: Fibroblast growth factor, Transforming growth factor alpha

transforming growth factor (TGF)

a group of proteins produced by the cells of a tumor that, when inoculated into a normal cell culture, causes a disorderly increase in the number of cells in the culture.

transforming growth factor

Any of a group of distinct polypeptides that have been isolated from virus-transformed rodent cells, which are capable of altering a cell's phenotype, causing fibroblasts to lose anchorage-dependence and stimulating angiogenesis

transforming growth factor (TGF),

n a group of proteins produced by cells of a tumor that, when inoculated into a normal cell culture, causes a disorderly increase in the number of cells in the culture.

transforming growth factor

one of the three growth factors released by platelets when they undergo the release reaction; plays a part in stimulating endothelial proliferation and repair of vascular smooth muscle.
References in periodicals archive ?
Genetic variation in transforming growth factor alpha: possible association of BamHI polymorphism with bilateral sporadic cleft lip and palate.
Transforming growth factor type beta 1 increases the expression of angiotensin II receptor type 2 by a SMAD- and p38 MAPK-dependent mechanism in skeletal muscle.
Transforming growth factor beta is an important immunomodulatory\ protein for human B lymphocytes.
Transforming growth factor beta contributes to progressive diabetic nephropathy.
Regulation and regulatory activities of transforming growth factor beta.
In the first part of this volume the basic concepts of transforming growth factor [Beta], or TGF[Beta], signaling in normal physiology and cancer pathobiology are described in 32 chapters, with topics that include TGF[Beta] availability, regulators of Smad activity by phosphorylation, activins and inhibins in cancer progression, and uterine sensitization associated Gene-1.
Fibrillin-1 is normally present in the matrix and regulates activation of transforming growth factor (TGF)-[beta].
Growth-differentiation factor 15 (GDF15) [4] is a member of the transforming growth factor [beta] (TGF-[beta]) cytokine superfamily.
Thus, the aim of this work is to present, by a literature review, the principal characteristics of transforming growth factor superfamily, in the regulation of the bone formation and wound healing bone.
Vitamin D has been shown to suppress the development Of autoimmunity in experimental animal models, possibly by stimulating production of transforming growth factor (TGF)-[beta]1 and interleukin-4, which in turn inhibits inflammatory T-cell activity (FASEB J.
4,5) The excess production of collagen has been linked to elevated levels of transforming growth factor beta (TGF-[beta]).
The formula was created using a special method of acid processing of the casein protein in cow's milk that preserves the biologic activity of the naturally occurring transforming growth factor (TGF)-[beta].

Full browser ?