transformation zone


Also found in: Acronyms.

trans·for·ma·tion zone

zone on the cervix at which squamous epithelium and columnar epithelium meet; changes location in response to a woman's hormonal status.

transformation zone

Gynecology The area of actively maturing epithelium between the current squamocolumnar junction–SCJ and the original squamous epithelium Composition Intermingled squamous and columnar epithelium–squamous metaplasia, islands of columnar epithelium, gland openings, Nabothian cyst; > 90% of neoplasia arises from the TZ; cervical colposcopy is inadequate unless the TZ is fully visualized; its location varies in relation to the ectocervix and endocervix, related to Pt age and degree of squamous metaplasia. See CIN.

transformation zone

Any area of the body where squamous epithelium meets columnar epithelium.
See: squamocolumnar junction
References in periodicals archive ?
Spitzer M, Chernys A, Seltzer V The use of large loop excision of the transformation zone in an innercity population.
Sensitivity of the cervical transformation zone to estrogen-induced squamous carcinogenesis.
This phase also enabled the nurse to recognise the abnormal transformation zone, perform biopsies and endocervical curettage.
Both LBC and CP were considered positive for the presence of transformation zone component when a minimum of 10 endocervical or metaplastic cells or 2 groups of 5 endocervical cells were seen.
However colposcopy did aid in assessing the transformation zone and the size of the lesion.
The 510(k) application used data from a clinical trial that measured cellularity, (whether a sufficient number of cells was collected), adequacy (the presence of cells representative of the endocervix and transformation zone - the two areas of the cervix where cervical cancer typically starts), reporting according to the Bethesda Classification System, and patient comfort.
The clinical trial measured cellularity, (whether a sufficient number of cells was collected), adequacy (the presence of cells representative of the endocervix and transformation zone -- the two areas of the cervix where cervical cancer typically starts), reporting according to the Bethesda Classification System, and patient comfort.
The most commonly used approach to the management of CIN 3 is loop electrosurgical excision of the cervical transformation zone (LEEP).
Instead, samples will simply be deemed either "satisfactory" or "unsatisfactory" with separate descriptors noting the presence or absence of transformation zone components, obscuring elements, or other factors that might limit interpretation.
Once inside, transformation zone begins and stretches across the casino to the oasis zone, an outdoor pool area.
We also assessed the effect on follow-up biopsy diagnoses of the presence or absence of an adequate endocervical cell/ transformation zone sample (EC/TZS) in Papanicolaou (Pap) test specimens from this selected older population.
But when the examination is done early in pregnancy and the entire area cannot be viewed, even with an endocervical speculum, it is appropriate to wait until the second trimester and repeat the colposcopy; in the second trimester, eversion of the cervical transformation zone may make complete visualization possible.

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