transformation zone


Also found in: Acronyms.

trans·for·ma·tion zone

zone on the cervix at which squamous epithelium and columnar epithelium meet; changes location in response to a woman's hormonal status.

transformation zone

Gynecology The area of actively maturing epithelium between the current squamocolumnar junction–SCJ and the original squamous epithelium Composition Intermingled squamous and columnar epithelium–squamous metaplasia, islands of columnar epithelium, gland openings, Nabothian cyst; > 90% of neoplasia arises from the TZ; cervical colposcopy is inadequate unless the TZ is fully visualized; its location varies in relation to the ectocervix and endocervix, related to Pt age and degree of squamous metaplasia. See CIN.

transformation zone

Any area of the body where squamous epithelium meets columnar epithelium.
See: squamocolumnar junction
References in periodicals archive ?
Spitzer M, Chernys A, Seltzer V The use of large loop excision of the transformation zone in an innercity population.
Sensitivity of the cervical transformation zone to estrogen-induced squamous carcinogenesis.
Removal of the transformation zone, with ablative or excisional treatment, is the recommended initial treatment
This phase also enabled the nurse to recognise the abnormal transformation zone, perform biopsies and endocervical curettage.
A loop is a very thin stainless steel wire of 2-3 cm used for excision of transformation zone with blended current, (cutting & coagulation) with low voltage output is used, tissue up to the depth of 10 mm or more can be removed.
14) Specimen adequacy was additionally reported, including the subcategories unsatisfactory and SBLB, considering (1) obscuring blood, (2) obscuring inflammation, (3) scant cellularity, (4) poor fixation, (5) mechanical damage, (6) cytolysis, (7) thick area, (8) too few squamous cells with predominantly endocervical cells, and (9) no endocervical or transformation zone component (SBLB ec-).
The loop size is chosen according to the size of the lesion and the transformation zone.
Two centimeters inside the anal canal is a transformation zone where the rectal columnar epithelium meets the anal squamous epithelium.
Reasons for referral included incomplete visualization of the transformation zone, significant discrepancy between cytology and histology, and high-grade lesions requiring laser or conization.
The CerCol collector is designed to capture a mirror image sample from 360 degrees of the endocervical canal, the ectocervical area and the transformation zone of the cervix with a single device.
The sampling procedure is designed to collect an adequate number of representative well-preserved epithelial cells including cells from the transformation zone.
Human papillomavirus DNA detection in ThinPrep Pap test vials is independent of cytologic sampling of the transformation zone.

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