transferrin saturation


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transferrin saturation

percentage of iron binding by the major plasma iron transport protein, measured in the blood to detect iron excess or deficiency. The normal transferrin saturation capacity in serum is 20% to 55%. See also total iron.

trans·fer·rin sat·ur·a·tion

(trans-fer'in sach'ŭr-ā'shŭn)
A calculation, expressed in percentages, of the amount of transferrin that is bound to iron. Determined by measuring serum iron and total iron-binding capacity (TIBC): serum iron × 100 = percentage saturation TIBC; helpful in differentiating anemias: a low transferrin saturation is associated with iron deficiency states; high with excess iron.
References in periodicals archive ?
Comparison of the serum ferritin and percentage of transferrin saturation as exposure markers of iron-driven oxidative stress-related disease outcomes.
Iron-deficiency anemia: The Kidney Dialysis International Guideline Organization defines iron deficiency warranting iron supplementation in CKD patients as a transferrin saturation of 30% or less and a serum ferritin of 50 ng/mL or less.
It also should not be forgotten that in HH, serum iron levels and the transferrin saturation rate can be within normal limits in cases with an excessive accumulation of iron in reticuloendothelial system organs and higher ferritin levels.
Relationships of serum ferritin, transferrin saturation, and HDE mutations and self-reported diabetes in the Hemochromatosis and Iron Overlaod Screening (HEIRS) study.
Serum iron, transferrin saturation, ferritin, and dietary data in age-related macular degeneration.
a) wound care, antibiotics and analgesics, treating lowered hemoglobin, transferrin saturation and ferritin levels
Iron deficiency indicators in children (8,11,14,17) Indicator/Age Normal Storage iron depletion Serum ferritin ([micro]g/L) Newborn 25-200 NA 1 month 200-600 NA 2-5 months 50-200 NA 6 months-3 years 7-140 <7 Serum iron ([micro]g/dL) Newborn 100-250 NA 1-12 months 40-100 NA 1-3 years 50-120 NA TIBC ([micro]g/dL) 1-12 months 100-400 360-390 1-3 years 100-400 360-390 % transferrin saturation 1-12 months 35-55% 15-30% 1-3 years 35-55% 15-30% FEP/ZPP (mg/dL) (hematoflourometer method) <30 30-99 Serum Transferrin Receptor (mg/L) 1 month-3 years <5.
The serum iron is low, transferrin concentration normal to low, and transferrin saturation low to normal.
The aim of our study was to assess the association of iron stores, reflected by transferrin saturation (TSAT) and ferritin, with the dispersion of corrected QT intervals (QTc) in patients undergoing hemodialysis.
15) Iron status, based on plasma ferritin and transferrin saturation, was considered generally satisfactory except in 15-year-old girls, among whom the percentage of iron deficiency was markedly higher (9.
051 21 NS NS NS, not significant; Q, quintile; TF, transferrin saturation.
The presence of abnormal transferrin saturation (TS) and serum ferritin (SF) levels provide evidence that increased risk has become the reality of iron overload.