We found that the sensitivity of the CHr was not superior to the MCH parameter or the transferrin saturation
, which is similar to the results of two other studies performed in hospital patients in which the authors also concluded that the CHr does not perform better than standard tests for IDA.
and serum ferritin arethe preferential indicators for estimation of iron status.
This is believed to occur when the transferrin saturation
exceeds a critical threshold and free iron is available for bacteria to use (Maynor & Brophy, 2007).
Comparison of the serum ferritin and percentage of transferrin saturation
as exposure markers of iron-driven oxidative stress-related disease outcomes.
Fasting serum transferrin saturation
and serum ferritin concentration are recommended as initial tests for HH (11) (SOR C).
It also should not be forgotten that in HH, serum iron levels and the transferrin saturation
rate can be within normal limits in cases with an excessive accumulation of iron in reticuloendothelial system organs and higher ferritin levels.
Relationships of serum ferritin, transferrin saturation
, and HDE mutations and self-reported diabetes in the Hemochromatosis and Iron Overlaod Screening (HEIRS) study.
Women with iron deficiency exhibited significantly lower levels of hemoglobin, mean corpuscular volume, ferritin, and transferrin saturation
in comparison with women who did not have iron deficiency anemia (Table 1).
All patients had a transferrin saturation
[greater than or equal to] 45 %, with 22.
Laboratory analysis revealed low serum iron (17 mg/dL), high serum ferritin (1343 [micro] g/mL), low serum transferrin saturation
(6%), undetectable serum ceruloplasmin (<4.
I'm using what's clinically readily available, assessing total iron binding capacity and transferrin saturation
4 g/l) levels and transferrin saturation
(4%), and a markedly elevated serum ferritin level (1 579 [micro]g/l).