transferrin


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Related to transferrin: Transferrin saturation, TIBC

transferrin

 [trans-fer´in]
a glycoprotein that binds and transports iron; most is produced in the liver. A similar compound produced in the intestinal mucosa is apoferritin.

trans·fer·rin

(trans-fer'in), [MIM*190000]
1. A nonheme β1-globulin of the plasma, capable of associating reversibly with up to 1.25 mcg iron per gram, and acting therefore as an iron-transporting protein.
2. A glycoprotein, found in mammalian milk (lactoferrin) and egg white (conalbumin, ovotransferrin), that binds and transports iron (Fe3+).
[trans- + L. ferrum, iron, + -ia]

transferrin

/trans·fer·rin/ (-fer´in) a glycoprotein mainly produced in the liver, binding and transporting iron, closely related to the apoferritin of the intestinal mucosa.

transferrin

(trăns-fĕr′ĭn)
n.
A beta globulin in blood serum that combines with and transports iron.

transferrin

[transfer′in]
a plasma protein that is essential in the transport of iron from the intestine into the bloodstream, making it available to the normoblasts in the bone marrow. It also may take part in a slower exchange with ferritin, hemosiderin, and other iron forms in the tissues. See also hemosiderin, iron transport.

transferrin

Siderophilin An 80-90 kD iron-transporting β-globulin that binds up to 2 atoms of Fe(III) with bicarbonate Ref range 2–4 g/L, US: 250-300 mg/dL. See Carbohydrate-deficient transferrin.

trans·fer·rin

(trans-fer'in)
1. A nonheme β1-globulin of the plasma, capable of associating reversibly with up to 1.25 mcg of iron per gram, and acting therefore as an iron-transporting protein.
2. A glycoprotein, found in mammalian milk (lactoferrin) and egg white (conalbumin, ovotransferrin), that binds and transports iron (Fe3+).
[trans- + L. ferrum, iron, + -ia]

transferrin

A blood protein (beta globulin) that can combine reversibly with iron and transport it to the cells.

transferrin

An iron-binding protein that carries iron in the blood plasma.

transferrin

human iron-binding protein found in the BLOOD PLASMA that reduces the availability of iron to a PATHOGEN.

Transferrin

A protein in blood plasma that carries iron derived from food intake to the liver, spleen, and bone marrow.
Mentioned in: Iron Tests

transferrin (transfer´in),

n a trace protein present in the blood that is essential in the transport of iron from the intestine into the bloodstream, making it available to the normoblasts in the bone marrow.

transferrin

a serum globulin that binds and transports iron.
References in periodicals archive ?
Role of transferrin receptor and the ABC transporters ABCB6 and ABCB7 for resistance and differentiation of tumor cells towards artesunate.
Iron [[micro]g/dl], TIBC [[micro]g/dl], UIBC [[micro]g/dl], Transferrin [[micro]g/dl], in water pipe smokers and cigarette smokers groups while no significant correlation were found in non-smokers group.
Biological variability of transferrin saturation and unsaturated iron binding capacity.
By averaging the subjects' transferrin levels, which had been assessed repeatedly - at 12, 14 and 16 years of age - the researchers estimated iron availability to the brain during adolescence.
In normal states, both intracellular ferritin and circulating transferrin are only partially saturated.
Bu evre transferrin saturasyonunun kontrolu ile saptanabilir.
Under normal conditions, only about 1 to 2% of transferrin is carbohydrate deficient.
One worth mentioning is the soluble transferrin receptor (sTfR) (6) which can help to distinguish between IDA and ACD.
The sTfR concentration has also been shown to be a more sensitive and less variable index of iron status than the more conventional serum iron, transferrin, and total iron-binding capacity (1-3).
1-antitrypsin, alkaline phosphatase (such as placental alkaline phosphatase), transferrin, and .
The serum iron is low, transferrin concentration normal to low, and transferrin saturation low to normal.