transferrin


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Related to transferrin: Transferrin saturation, TIBC

transferrin

 [trans-fer´in]
a glycoprotein that binds and transports iron; most is produced in the liver. A similar compound produced in the intestinal mucosa is apoferritin.

trans·fer·rin

(trans-fer'in), [MIM*190000]
1. A nonheme β1-globulin of the plasma, capable of associating reversibly with up to 1.25 mcg iron per gram, and acting therefore as an iron-transporting protein.
2. A glycoprotein, found in mammalian milk (lactoferrin) and egg white (conalbumin, ovotransferrin), that binds and transports iron (Fe3+).
[trans- + L. ferrum, iron, + -ia]

transferrin

/trans·fer·rin/ (-fer´in) a glycoprotein mainly produced in the liver, binding and transporting iron, closely related to the apoferritin of the intestinal mucosa.

transferrin

(trăns-fĕr′ĭn)
n.
A beta globulin in blood serum that combines with and transports iron.

transferrin

[transfer′in]
a plasma protein that is essential in the transport of iron from the intestine into the bloodstream, making it available to the normoblasts in the bone marrow. It also may take part in a slower exchange with ferritin, hemosiderin, and other iron forms in the tissues. See also hemosiderin, iron transport.

transferrin

Siderophilin An 80-90 kD iron-transporting β-globulin that binds up to 2 atoms of Fe(III) with bicarbonate Ref range 2–4 g/L, US: 250-300 mg/dL. See Carbohydrate-deficient transferrin.

trans·fer·rin

(trans-fer'in)
1. A nonheme β1-globulin of the plasma, capable of associating reversibly with up to 1.25 mcg of iron per gram, and acting therefore as an iron-transporting protein.
2. A glycoprotein, found in mammalian milk (lactoferrin) and egg white (conalbumin, ovotransferrin), that binds and transports iron (Fe3+).
[trans- + L. ferrum, iron, + -ia]

transferrin

A blood protein (beta globulin) that can combine reversibly with iron and transport it to the cells.

transferrin

An iron-binding protein that carries iron in the blood plasma.

transferrin

human iron-binding protein found in the BLOOD PLASMA that reduces the availability of iron to a PATHOGEN.

Transferrin

A protein in blood plasma that carries iron derived from food intake to the liver, spleen, and bone marrow.
Mentioned in: Iron Tests

transferrin (transfer´in),

n a trace protein present in the blood that is essential in the transport of iron from the intestine into the bloodstream, making it available to the normoblasts in the bone marrow.

transferrin

a serum globulin that binds and transports iron.
References in periodicals archive ?
Is serum transferrin receptor useful for detecting iron-deficiency in anaemic patients with chronic inflammatory diseases?
Hepatic transferrin gene expression was downregulated in group-II, in comparison with the control group, whereas groups I and III revealed no results (Figure 1c, 4c).
Trimester wise changes in levels of transferrin and ferritin in group I and II were also analyzed.
Transferrin is the main iron transport protein found in the circulation.
Transferrin was conjugated with amine terminated magnetic nanoaprticles by two step glutaraldehyde method.
Studies have previously revealed lower levels of iron and transferrin saturation in obese as compared to the normal weight individuals and a negative correlation of transferrin saturation with BMI.
Iron [[micro]g/dl], TIBC [[micro]g/dl], UIBC [[micro]g/dl], Transferrin [[micro]g/dl], in water pipe smokers and cigarette smokers groups while no significant correlation were found in non-smokers group.
Distribution of Transferrin saturation level TSAT% Number of patients Percentage 0.
Comparison of the serum ferritin and percentage of transferrin saturation as exposure markers of iron-driven oxidative stress-related disease outcomes.
A limitation for the use of CDT resides in the fact that abnormal serum transferrin glycoforms (with different numbers of sialic acid residues) can be found in carbohydrate deficient glycoprotein syndromes.
Paul Thompson and his colleagues from the University of California, Los Angeles, measured levels of transferrin, a protein that transports iron throughout the body and brain, in adolescents.