transferrin


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Related to transferrin: Transferrin saturation, TIBC

transferrin

 [trans-fer´in]
a glycoprotein that binds and transports iron; most is produced in the liver. A similar compound produced in the intestinal mucosa is apoferritin.

trans·fer·rin

(trans-fer'in), [MIM*190000]
1. A nonheme β1-globulin of the plasma, capable of associating reversibly with up to 1.25 mcg iron per gram, and acting therefore as an iron-transporting protein.
2. A glycoprotein, found in mammalian milk (lactoferrin) and egg white (conalbumin, ovotransferrin), that binds and transports iron (Fe3+).
[trans- + L. ferrum, iron, + -ia]

transferrin

(trăns-fĕr′ĭn)
n.
A beta globulin in blood serum that combines with and transports iron.

transferrin

Siderophilin An 80-90 kD iron-transporting β-globulin that binds up to 2 atoms of Fe(III) with bicarbonate Ref range 2–4 g/L, US: 250-300 mg/dL. See Carbohydrate-deficient transferrin.

trans·fer·rin

(trans-fer'in)
1. A nonheme β1-globulin of the plasma, capable of associating reversibly with up to 1.25 mcg of iron per gram, and acting therefore as an iron-transporting protein.
2. A glycoprotein, found in mammalian milk (lactoferrin) and egg white (conalbumin, ovotransferrin), that binds and transports iron (Fe3+).
[trans- + L. ferrum, iron, + -ia]

transferrin

A blood protein (beta globulin) that can combine reversibly with iron and transport it to the cells.

transferrin

An iron-binding protein that carries iron in the blood plasma.

transferrin

human iron-binding protein found in the BLOOD PLASMA that reduces the availability of iron to a PATHOGEN.

Transferrin

A protein in blood plasma that carries iron derived from food intake to the liver, spleen, and bone marrow.
Mentioned in: Iron Tests
References in periodicals archive ?
When only patients with new diagnoses were analyzed, a transferrin saturation of less than 45% was 100% sensitive for excluding patients with the C282Y/C282Y genotype.
In our study, patients with A2 albuminuria presented higher concentrations of most studied markers of both glomerular (serum cystatin C, urine IgG, and transferrin) and tubular damage (urine and serum NGAL, urine KIM-1), as well as lower serum concentrations of uromodulin.
Sanchez et al., "Varying iron release from transferrin and lactoferrin proteins.
Transferrin receptor (mg/dl)###7.31+-1.81###10.13+-2.58###13+-4.12###15.93+-3.58###<0.001
Hepatic transferrin gene expression was downregulated in group-II, in comparison with the control group, whereas groups I and III revealed no results (Figure 1c, 4c).
Hirama et al., "Molecular cloning of transferrin receptor 2.
Finally a correlation test was run between the BMI and the dependent variables, namely, ferritin, iron, transferrin, TIBC, and CRP (Table 3).
The mean serum transferrin and ferritin in control group was 293 [+ or -] 32.55 mg/dl and 87.6 [+ or -] 16.65 [micro]g/l, respectively.
This study used Western blotting to detect transferrin and ENOSF1 expression.
The absorption of iron is unusually increased because the transferrin receptors are over expressed in cancer state (Qian et al., 2002).
TRF-DOX is a combination of the iron-binding glycoprotein, transferrin, and Doxorubicin resulting in targeted delivery to tumours with the reduction of serious side effects.