transferase


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transferase

 [trans´fer-ās]
an enzyme that catalyzes the transfer, from one molecule to another, of a chemical group that does not exist in free state during the transfer.

transferase

/trans·fer·ase/ (trans´fer-ās) a class of enzymes that transfer a chemical group from one compound to another.

transferase

(trăns′fə-rās′, -rāz′)
n.
Any of various enzymes that catalyze the transfer of a chemical group, such as a phosphate or amine, from one molecule to another.

transferase

[trans′fərās]
Etymology: L, transferre + Fr, diastase, enzyme
any of a group of enzymes that catalyzes the transfer of a chemical group or radical, such as the phosphate, methyl, amine, or keto groups, from one molecule to another.

transferase

Any enzyme that catalyses the movement of atoms or groups of atoms from one molecule to another. A kinase adds a phosphate group to a substrate such as an amino acid.

transferase

any enzyme that catalyses the transfer of a chemical group such as amino, methyl or alkyl from one SUBSTRATE to another substrate.

transferase (trans´fərās´),

n a group of enzymes that catalyze the transfer of a chemical group or radical from one molecule to another.

transferase

an enzyme that catalyzes the transfer, from one molecule to another, of a chemical group that does not exist in free state during the transfer.

gamma glutamyl transferase (GGT)
found in the cell membrane in most tissues, but particularly high levels are present in liver (bile duct cells, hepatocytes) and kidney (renal convoluted tubular cells). Increased serum levels occur primarily with cholestasis.
glucuronyl transferase
enzyme which converts bilirubin to a soluble glucuronide.
glutathione S-t's
widely distributed enzymes catalyzing the detoxification of many compounds but particularly xenobiotics by linkage of the cysteine moiety of glutathione with the compound.
ornithine carbamoyl transferase (OCT)
catalyzes the transfer of carbamoyl, as from carbamoylphosphate to l-ornithine to form orthophosphate and citrulline in the synthesis of urea. Found almost exclusively in the liver. Determination of serum levels is used as an indicator of hepatocellular damage, particularly in cattle, sheep and pigs.
peptidyl transferase
a ribosomal enzyme that transfers the growing peptide from its carrier tRNA to the α-amino group of the amino acid residue of the aminoacyl-tRNA specified by the next codon of the mRNA.
References in periodicals archive ?
Studies of these interactions helped explain why 3-FTyr GST exhibits spectral and kinetic properties distinct from the native GSH transferase.
Glutathione S-transferases (GSTs), also known as the glutathione transferases, comprise a large and diverse family of enzymes with a wide phylogenetic distribution.
To correlate the serum Gamaglutamyl transferase activity with lipid ratios in myocardial infarction patients and healthy subjects.
Characterization of the promoters of Epsilon glutathione transferases in the mosquito Anopheles gambiae and their response to oxidative stress.
Katsuya H, Misumi M, Ohtani Y, Miike T Postanesthetic acute renal failure due to carnitine palmityl transferase deficiency.
Isoenzyme specific quantitative immunoassays for cytosolic glutathione transferases and measurement of the enzymes in blood plasma from cancer patients and in tumor cell lines.
Serum alanine transferase levels declined in patients receiving rosglitazone, perhaps because the drug decreased liver fat content.
The woman's values were aspartate amino transferase (ASAT) 48 IU/L (normal <26); alanine amino transferase (ALAT) 29 IU/L (normal <27); gamma glutamyl transferase (g-GT) 32 IU/L (normal <200); and lactate dehydrogenase (LDH) 517 IU/L (normal <250).
In addition to PGxPredict:RITUXIMAB, PGxHealth provides the following genetic tests to practitioners: FAMILION([R]), a genetic test designed to identify mutations in people with inherited cardiac channelopathies such as Long QT Syndrome (LQTS) and Brugada Syndrome; PGxPredict[TM]:WARFARIN, a pharmacogenetic test that measures variation in 2 genes related to response to warfarin; a pharmacogenetic assay that tests for mutations in the thiopurine S-methyl transferase (TPMT) gene, exclusively licensed from St.
29 November 2011 - US biopharmaceutical firm OncoVista Innovative Therapies Inc (OTCBB:OVIT) said on Monday it had mandated consulting and clinical research organisation Oncology Therapeutic Development (OTD) to launch a Phase Ib clinical study of Cordycepin related to Pentostatin to treat terminal deoxynucleotidyl transferase (TdT)-positive refractory leukemia.
Syngenta Participations AG (Basle, Switzerland) has patented a DNA construct comprising an expression cassette having a constitutive promoter which functions in plant cells operably linked to a maize alcohol dehydrogenase intron, a DNA sequence of a gene encoding a Cry 1Ab protein, and a terminator functional in plants and optionally further comprising a second cassette including a promoter which functions in plants operably linked to a maize alcohol dehydrogenase intron, a DNA sequence of a gene encoding for phosphinothricin acetyl transferase, and a terminator functional in plants wherein the two cassettes are transcribed in the same direction.
PGxHealth provides the following genetic tests to practitioners: FAMILION([R]), a genetic test designed to identify mutations in people with inherited cardiac channelopathies such as Long QT Syndrome (LQTS) and Brugada Syndrome; PGxPredict: WARFARIN, a pharmacogenetic test that measures variation in 2 genes related to response to warfarin; and a pharmacogenetic assay that tests for mutations in the thiopurine S-methyl transferase (TPMT) gene, exclusively licensed from St.