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a factor occurring in sensitized lymphocytes that has the capacity to transfer delayed hypersensitivity to a normal (nonreactive) individual. It confers cell-mediated immunity and therefore has been found to be useful in treating conditions in which there is a disorder of immune response. As an adjunct to antibiotic therapy it is useful in the treatment of such antibiotic-resistant diseases as candidiasis, coccidioidomycosis, and leprosy.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
1. the transfer gene of a conjugative plasmid, especially of the resistance plasmid;
2. a dialyzable extract that is obtained from the leukocytes of a person with a delayed-type sensitivity and that, after injection into the skin of a nonsensitive person, transfers the specific sensitivity to the recipient;
3. Synonym(s): elongation factor
Farlex Partner Medical Dictionary © Farlex 2012
Any of various small proteins that are obtained from donors with cell-mediated immunity to certain antigens and can confer this immunity when given to nonimmune recipients.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
trans·fer fac·tor(trans'fĕr fak'tŏr)
1. The transfer gene of a conjugative plasmid, especially of the resistance plasmid.
2. A dialyzable extract that is obtained from the leukocytes of a person with a delayed-type sensitivity and that, following injection into the skin of a nonsensitive person, transfers the specific sensitivity to the recipient.
3. Synonym(s): elongation factor.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
transfer factorA LYMPHOKINE released by T cells that activates MACROPHAGES and prompts them to attack fungi.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005