transfer factor


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transfer factor

 (TF)
a factor occurring in sensitized lymphocytes that has the capacity to transfer delayed hypersensitivity to a normal (nonreactive) individual. It confers cell-mediated immunity and therefore has been found to be useful in treating conditions in which there is a disorder of immune response. As an adjunct to antibiotic therapy it is useful in the treatment of such antibiotic-resistant diseases as candidiasis, coccidioidomycosis, and leprosy.

trans·fer fac·tor

1. the transfer gene of a conjugative plasmid, especially of the resistance plasmid;
2. a dialyzable extract that is obtained from the leukocytes of a person with a delayed-type sensitivity and that, after injection into the skin of a nonsensitive person, transfers the specific sensitivity to the recipient;
3. Synonym(s): elongation factor

transfer factor

n.
Any of various small proteins that are obtained from donors with cell-mediated immunity to certain antigens and can confer this immunity when given to nonimmune recipients.

trans·fer fac·tor

(trans'fĕr fak'tŏr)
1. The transfer gene of a conjugative plasmid, especially of the resistance plasmid.
2. A dialyzable extract that is obtained from the leukocytes of a person with a delayed-type sensitivity and that, following injection into the skin of a nonsensitive person, transfers the specific sensitivity to the recipient.
3. Synonym(s): elongation factor.

transfer factor

A LYMPHOKINE released by T cells that activates MACROPHAGES and prompts them to attack fungi.
References in periodicals archive ?
Comparative study of transfer factor and acyclovir in the treatment of herpes zoster.
It is shown in Figure 4(b) that, in the vicinity of the point of panel modal density where the transfer factor is approximately equal to 1.0, the resonance frequencies of the (0,0,1) enclosure-controlled mode and the (3,1) panel-controlled mode which deviate from uncoupled resonance frequencies are greater than others, respectively.
Morgan, "Acquired chronic candidiasis treated with transfer factor," British Journal of Dermatology, vol.
The transfer factors (see Table 2) are from 0.87 (A2M) to 1.07 (C4), with an average of 0.94 (SD 0.05).
[j.sub.iw] Colburn's heat transfer factor for the fluids flow in window zone
Table 2--Creation of the Knowledge Transfer Factor Description Knowledge Communality Transfer Factor V19--Extent to which the .884 .781 knowledge received from the Headquarters is used V20--Extent to which the .884 .781 knowledge received from other subsidiaries is used KMO 0.50 Explained Variance 78.0% Source: Factorial analysis results.
(1993) Influence of smoking habits on change in carbon monoxide transfer factor over 10 years in middle aged men.
Among the 46 allegations, Dr Wakefield was accused of allowing one patient - known as Child 10 - to be given an experimental drug, known as "Transfer Factor", with the view to it becoming a measles vaccine.
This one-fifth bioaccumulation and egg transfer factor is well within the range found for other fat-soluble contaminants.
Although none of the patients reported chronic respiratory problems at follow-up, "...only 62%...had respiratory function within the normal limits." Specifically, "...23% had a restrictive pattern, and 15% had isolated transfer factor impairment."