transcytosis


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trans·cy·to·sis

(tranz'sī-tō'sis),
A mechanism for transcellular transport in which a cell encloses extracellular material in an invagination of the cell membrane to form a vesicle (endocytosis), then moves the vesicle across the cell to eject the material through the opposite cell membrane by the reverse process (exocytosis). The transport mechanism by which most proteins reach the Golgi apparatus or the plasma membrane; the vesicles targeted toward lysosomes and secretory storage granules appear to be coated with clathrin.
Farlex Partner Medical Dictionary © Farlex 2012

transcytosis

A type of caveolae-mediated vesicular trafficking, in which caveolae transport proteins from the luminal side of an endothelial cell to the interstitial compartment for subsequent uptake by surrounding tissue.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

trans·cy·to·sis

(tranz-sī-tō'sis)
A mechanism for transcellular transport in which a cell encloses extracellular material in an invagination of the cell membrane to form a vesicle (endocytosis), then moves the vesicle across the cell to eject the material through the opposite cell membrane by the reverse process (exocytosis).
Synonym(s): vesicular transport.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

transcytosis

(trănz-sī-tō′sĭs)
The ferrying of a substance across a cell membrane in coated vesicles.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
CNS delivery via adsorptive transcytosis. AAPS J 2008;10:455-72.
A new function for the LDL receptor: Transcytosis of LDL across the blood-brain barrier.
Tuma, "Alcohol-induced defects in hepatic transcytosis may be explained by impaired dynein function," Molecular and Cellular Biochemistry, vol.
Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis. Am J Pathol.
The SRC family protein tyrosine kinase p62yes controls polymeric IgA transcytosis in vivo.
Feng et al., "Engineered antibody domains with significantly increased transcytosis and half-life in macaques mediated by FcRn," mAbs, vol.
Tan, "Toll-like receptor 2-mediated peptidoglycan uptake by immature intestinal epithelial cells from apical side and exosome-associated transcellular transcytosis," Journal of Cell Physiology, vol.
Insulin production by cells in the brain is somewhat controversial, although insulin is delivered from the blood to the brain by receptor-mediated transcytosis. The insulin receptor rarely induces glucose uptake by brain cells.
Impaired autophagy in the RPE leads to cell transcytosis and exocytosis and early signs of retinal degeneration [4].
TNF-[alpha] boosts atherosclerosis development by promoting the transcytosis of low-density lipoprotein (LDL) across endothelial cells, thus contributing to the reservoir of LDL in vascular walls [31].
Li et al., "Palmitate-induced inflammatory pathways in human adipose microvascular endothelial cells promote monocyte adhesion and impair insulin transcytosis," American Journal of Physiology--Endocrinology and Metabolism, vol.

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