transcytosis


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trans·cy·to·sis

(tranz'sī-tō'sis),
A mechanism for transcellular transport in which a cell encloses extracellular material in an invagination of the cell membrane to form a vesicle (endocytosis), then moves the vesicle across the cell to eject the material through the opposite cell membrane by the reverse process (exocytosis). The transport mechanism by which most proteins reach the Golgi apparatus or the plasma membrane; the vesicles targeted toward lysosomes and secretory storage granules appear to be coated with clathrin.

transcytosis

A type of caveolae-mediated vesicular trafficking, in which caveolae transport proteins from the luminal side of an endothelial cell to the interstitial compartment for subsequent uptake by surrounding tissue.

trans·cy·to·sis

(tranz-sī-tō'sis)
A mechanism for transcellular transport in which a cell encloses extracellular material in an invagination of the cell membrane to form a vesicle (endocytosis), then moves the vesicle across the cell to eject the material through the opposite cell membrane by the reverse process (exocytosis).
Synonym(s): vesicular transport.

transcytosis

(trănz-sī-tō′sĭs)
The ferrying of a substance across a cell membrane in coated vesicles.
References in periodicals archive ?
Majority of BBB technologies (53%) are based on the process of receptor mediated transcytosis (RMT).
Transcytosis of human immunodeficiency virus 1 across the placenta is enhanced by treatment with tumour necrosis factor alpha.
Differential role for CD23 splice forms in apical to basolateral transcytosis of IgE/allergen complexes.
Transcytosis of Streptococcus iniae through skin epithelial barriers: an in vitro study.
They can also act as ideal rigid building blocks to synthesize special surface architectures They hold promise in tissue engineering, tissue targeting applications (262,263), drug solubilisation (264) controlled drug release (265) and moreover, their interesting nanoscopic architecture might allow easier passage across biological barriers by transcytosis.
It is known that LDL could pass, via transcytosis, through the vascular endothelium to reach the subendothelial space.
Although there are no data regarding these parameters for sensory neurons, they affect endo- and transcytosis of nanosized materials (e.
Among these transcytosis is of special interest; by this mechanism, intact proteins, immumoglobulins, hormones and growth factors can cross the mammary epithelium and be secreted intact in the milk (Hunziker and Kraehenbuhl, 1998; Monks and Neville, 2004).
Other peculiar features of these cerebral capillaries are non feasibility of transcytosis (due to fewer endocytic vesicles), greater number of mitochondria, presence of thick basement membrane and presence of astrocytic end foot (27).
6,7) Infectious agents may enter the CNS within infected migratory macrophages, or they may gain access by transcytosis across the blood-brain-barrier or by intraneuronal transfer from peripheral nerves.
Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration.
Removal of osteoclast bone resorption products by transcytosis.

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