transcytosis


Also found in: Encyclopedia, Wikipedia.

trans·cy·to·sis

(tranz'sī-tō'sis),
A mechanism for transcellular transport in which a cell encloses extracellular material in an invagination of the cell membrane to form a vesicle (endocytosis), then moves the vesicle across the cell to eject the material through the opposite cell membrane by the reverse process (exocytosis). The transport mechanism by which most proteins reach the Golgi apparatus or the plasma membrane; the vesicles targeted toward lysosomes and secretory storage granules appear to be coated with clathrin.

transcytosis

A type of caveolae-mediated vesicular trafficking, in which caveolae transport proteins from the luminal side of an endothelial cell to the interstitial compartment for subsequent uptake by surrounding tissue.

trans·cy·to·sis

(tranz-sī-tō'sis)
A mechanism for transcellular transport in which a cell encloses extracellular material in an invagination of the cell membrane to form a vesicle (endocytosis), then moves the vesicle across the cell to eject the material through the opposite cell membrane by the reverse process (exocytosis).
Synonym(s): vesicular transport.

transcytosis

(trănz-sī-tō′sĭs)
The ferrying of a substance across a cell membrane in coated vesicles.
References in periodicals archive ?
A new function for the LDL receptor: Transcytosis of LDL across the blood-brain barrier.
To assess cell monolayer permeability and transcytosis, 3-[micro]m pore Transwell inserts for 24-well microplates (ThincertsTM, Greiner Bio-One, Austria) were used.
Increased transcytosis of lipoproteins is the initial event in atherogenesis.
Colostrogenesis: candidate genes for IgG1 transcytosis mechanisms in primary bovine mammary epithelial cells.
Moreover, endocytosis and transcytosis have also been proposed as the most common transport mechanisms for NPs at the blood-brain barrier (Kreuter 2014).
Its researchers hypothesized that smaller sequences within the 80 kDa protein would bind to specific receptors for this protein thus initiating transport across the BBB through a process known as Receptor Mediated Transcytosis.
In mammals, AVP accumulates AQP2 at the apical membrane mainly by translocation of intracellular subapical storage vesicles, and also by indirect transcytosis from the basolateral membrane (Sasaki, 2012; Yui et al.
This process of drifting (margination), lodging (firm adhesion) and penetration (EPR, transcytosis, and paracytosis) is fundamentally enabled by the shape (disks, resembling platelets), size (3-micrometer diameter, 200 nm thickness), surface charge, and density.
sup][6] reported that GP-60 activation mediates albumin transcytosis in endothelial cells via the tyrosine kinase-dependent pathway.
A likely candidate for the changes in IgA seen with exercise is sympathetic stimulation (19), which could increase transcytosis of IgA from plasma cells through epithelial cells.
The molecule suppresses a barrier-crossing mechanism called transcytosis, a process by which substances are carried through the BBB in bubbles called vesicles.

Full browser ?