We have previously shown that APOBEC1-catalyzed editing in the transcriptome
of macrophages leads to the generation of populations that are heterogeneous, and functionally diverse, enabling rapid population adaptation to different environmental settings.
The average MAF was 18% in putative SNPs identified from the skin transcriptomes
of Cashmere goats (Figure 5).
often have rearranged genomes and harbor transcripts that are not encoded in a reference genome, like those derived from tumor viruses or microbes.
Mapping and quantifying mammalian transcriptomes
Since 2004, the company has been involved with numerous sequencing projects such as transcriptomes
, metagenomics and notably sequencing the oil palm genome as a member of the consortium with Washington University and Orion Genomics.
Novel high-throughput and deep-sequencing technologies are currently being used in genomic research, and provide new strategies for analyzing the functional complexities of transcriptomes
or of the transcribed DNA of an organism, thereby generating functional genomic data.
We believe that this is a great opportunity to demonstrate the unique utility of MPSS(TM) in profiling the complete transcriptome
of an organism whose genome is only now being sequenced," said Dr.
The core technology used in this product enriches for mRNA in NGS libraries, and can be applied to transcriptomes
extracted from pure and mixed microbial cultures in a simple workflow.
After initial validation by qPCR in the source transcriptomes
used for NGS, further validation of the targets will be done through loss- and gain-of-function assays.
announced today the publication of a comprehensive study led by scientists at the National Cancer Institute and the Ludwig Institute for Cancer Research that used Lynx's Massively Parallel Signature Sequencing, or MPSS(TM) technology, to characterize the transcriptomes
, or complete gene expression profiles, of two human cell lines.
The National Center for Genome Resources (NCGR) and the Gordon and Betty Moore Foundation's (GBMF) Marine Microbiology Initiative (MMI) today announced a new research program to sequence the transcriptomes
of approximately 750 marine microbial eukaryotes.
I will perform an in vivo analysis of transcriptomes
of infected macrophages and neutrophils using zebrafish larvae with these cell types specifically labelled.