Molecular science company Caris Life Sciences reported on Friday the receipt of the US Food and Drug Administration's (FDA) breakthrough device designation for the MI Transcriptome
companion diagnostic (CDx) test for detection of novel FGFR biomarkers including gene fusions in solid tumors.
[ClickPress, Fri Mar 15 2019] Global RNA transcriptome
profiling test is a powerful tool to understand expression patterns at cellular levels for identifying the genes having similar expression patterns.
As the spleen is an important peripheral immune organ, its transcriptome
characteristics can be used to evaluate immune responses of pigs infected with different pathogens (Chen et al., 2009; Li et al., 2010; Zhang et al., 2017).
For instance, a basic transcriptome
generated from gonad tissue of a shellfish at different maturational stages could be used by other laboratory groups to identify genetic markers, develop quantitative polymerase chain reaction assays, design primers to identify homologs in other species, and create an in silico reference for shotgun proteomic analysis.
Likewise, profiling a tumor's transcriptome
requires a more precise approach.
These cleaned sequences were used to assemble a transcriptome
using the Trinity software package (ver.
In this study, the authors chose the most relevant tissue (skeletal muscle biopsy for NMDs) based on disease phenotype and transcriptome
expressional profile principal component analysis for RNA-seq.
Chehade's project entitled "Impact of Proton Pump Inhibitors on the Esophageal Transcriptome
in Eosinophilic Esophagitis Subtypes" will receive funding of $70,000 per year for two years (a total of $140,000).
comparison has also been conducted for evolution analysis and searching economically important traits in some genome unavailable crops .
Analysis of the transcriptome
of peripheral blood mononuclear cells (PBMCs) has successfully elucidated the mechanisms of numerous complex diseases and vaccination models [7-10].
nipae, including external morphology, physiology characteristic, biological habits, raising management, disease and pest control technique [3-6], multiple mating , transcriptome
immune analysis , and rapid identification of species based on cytochrome c oxidase subunit I (COI) and internal transcribed spacer (ITS) .