transcriptional profiling

transcriptional profiling

The study of the complete set of RNA transcripts that are made from an organism's DNA.
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3 MOLECULAR PATHOLOGY AND TRANSCRIPTIONAL PROFILING IN EARLY DRUG DEVELOPMENT (Cornelia Liedtke, Lajos Pusztai, and W.
Ansell Professor of Dermatology at Tufts University School of Medicine and Senior Author stated, "In addition to the these encouraging safety and efficacy results seen with 28-days of treatment with INCB18424, transcriptional profiling data demonstrate that topical INCB18424 inhibits two key pathways, Th1 and Th17, that play important roles in the pathogenesis of psoriasis.
Our ability to perform MPSS(TM) transcriptional profiling of CD4+ lymphocytes after expression of HIV-1 regulatory genes or infection by HIV-1 should prove critically important in determining how and why these immune cells are depleted in HIV-1-infected patients," said Dr.
Identification of Testis-Specific Male Contraceptive Targets: Insights from Transcriptional Profiling of the Cycle of the Rat Seminiferous Epithelium and Purified Testicular Cells: Daniel S.
Transcriptional profiling, which is used to trace differences in gene expression between healthy and diseased tissues, revealed production of the MMP-8 enzyme in endothelial cells and smooth muscle cells that compose human blood vessels.
Examples of some of the applications tSMS will enable are whole tumor resequencing, quantitative transcriptional profiling, genome wide methylation studies, and candidate region resequencing.
Protein folding, 3-D structure studies and transcriptional profiling determine which genes are active, producing proteins in a particular cell type, development stage, or disease state.
Libermann has a strong interest in developing microarray technologies for transcriptional profiling, detection of genetic mutations, pharmacogenomics, and proteomics.
CXR Biosciences plans to use the statistical analysis tools in the Resolver system to generate high-quality data to support its toxicological research using transcriptional profiling.
Examples of some of the applications tSMS(TM) will enable are whole tumor resequencing, quantitative transcriptional profiling, genome wide methylation studies, and candidate region resequencing.
Ryan spent 11 years at Wyeth where he most recently held the position of Senior Vice President of Translational Research and Head of the Department of Experimental Medicine, which was created to explore new technologies such as pharmacogenomics in exploratory clinical trials, and to work closely with FDA on the use of transcriptional profiling in clinical trials.
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