transcription factors

transcription factors

Proteins that initiate the transcription of genes.
References in periodicals archive ?
Scientists have created iPSCs not with transcription factors, but by adding a cocktail of chemicals to the cells.
Scientists have created iPSCs not with transcription factors, but by adding a cocktail of chemicals to the cells The latest study offers a third way to turn skin cells into stem cells by directly manipulating the cells' genome using CRISPR gene regulation techniques.
Rosengart, a team of researchers showed that administration of a cocktail made of transcription factors Gata4, Mef2c and Tbx5 (GMT) resulted in less scar tissue, or fibrosis, and up to a 50 percent increase in cardiac function in small animal models of the disease.
This study identifies how the modification of the DNA structure affects the binding of transcription factors, and this increases our understanding of how genes are regulated in cells and further aids us in deciphering the grammar written into DNA," study co-author Jussi Taipale from Karolinska Institutet in Sweden said in a (http://ki.
This form of B-precursor acute lymphoblastic leukemia (B-ALL) features genetic changes to two transcription factors known as DUX4 and ERG, proteins that closely control the activities of other crucial genes in human blood cells.
WRKY transcription factors are involved in diverse life processes in plants.
Transcription factors are essential for the regulation of gene expression.
In this article I will overview the recent progress of our studies on the regulation of genome transcription focusing on the regulatory roles and networks of all transcription factors in a single model organism E.
Scientists who use the techniques--and in many cases helped devise them--explain methods for transcriptional factor trafficking and post-translational modification, the cytoplasmic-nuclear trafficking of transcription factors, post-translational modification and impact on function, and protocols for optimizing functional assays.
5) describes the transformation of "skin fibroblast cells from mice into working neurons by using viruses to insert genes that encode transcription factors.
Equivalence between the products of ANT and SCNT obscures the biological distinction between transcription factors and coding genes.
This model of action is consistent with the ability of NS1 expression to prevent activation of transcription factors involved in the induction of IFN[alpha]/[beta] synthesis, including IRF3 (16).

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