E2F1

(redirected from transcription factor E2F)

E2F1

A gene on chromosome 20q11.2 that encodes a member of the E2F family of DNA-binding transcription factors, which play a key role in regulating the cell cycle and tumour suppressor proteins. E2Fs are targets of transforming proteins of small DNA tumour viruses.
Mentioned in ?
References in periodicals archive ?
Other subjects include computational methods for protein structural class prediction, fundamentals of natural computation in living systems, and combining computational and experimental analysis for the prediction of transcription factor E2F regulatory elements in the human gene promoter.
E2F Decoy is an oligonucleotide that binds to and inactivates the pivotal cell-cycle transcription factor E2F.
At the bottom of this pathway lie the functions of the transcription factor E2F, whose activity in the cell is regulated by the protein product of the retinoblastoma gene, Rb whose function is lost in about 40% of all human cancers.
CGT003 is E2F Decoy, an oligonucleotide that binds to and inactivates the pivotal cell-cycle transcription factor E2F, administered in Corgentech's proprietary drug-delivery device.
A cDNA encoding a pBR-Binding protein with properties of the transcription factor E2F.
CGT021 is E2F Decoy, an oligonucleotide that binds to and inactivates the pivotal cell-cycle transcription factor E2F, administered in Corgentech's drug-delivery device.
E2F Decoy is an oligonucleotide, or short strand of DNA, that binds to and inactivates the pivotal transcription factor E2F, which is responsible for activating dozen or more genes that must be turned on during vascular cell growth and multiplication.

Full browser ?