transcriptase


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transcriptase

 [trans-krip´tās]
RNA polymerase; an enzyme that catalyzes the synthesis (polymerization) of RNA from ribonucleoside triphosphates, with DNA serving as a template.
reverse transcriptase see reverse transcriptase.

tran·scrip·tase

(tran-skrip'tās),
A polymerase associated with the process of transcription; may be RNA dependent or DNA dependent.
[L. transcribo, pp. transcriptum, to copy, + -ase]

transcriptase

/trans·crip·tase/ (-krip´tās) a DNA-directed RNA polymerase; an enzyme that catalyzes the synthesis (polymerization) of RNA from ribonucleoside triphosphates, with DNA serving as a template.
reverse transcriptase  see at R.

transcriptase

(trăn-skrĭp′tās, -tāz)
n.
1. A polymerase that catalyzes the formation of RNA from a DNA template in the process of transcription.
2. Reverse transcriptase.

transcriptase

[transkrip′tās]
an enzyme that induces transcription.

tran·scrip·tase

(tran-skrip'tās)
A polymerase associated with the process of transcription; especially the DNA-dependent RNA polymerase.
[L. transcribo, pp. transcriptum, to copy, + -ase]

transcriptase

Any enzyme that catalyses transcription of a molecule, as in the process of producing a copy of RNA from DNA. Reverse transcriptase is an enzyme found in viruses, such as HIV, that catalyses DNA from an RNA template-the reverse of the usual procedure.

transcriptase

an RNA POLYMERASE (either RNA- or DNA-dependent) involved in TRANSCRIPTION.

tran·scrip·tase

(tran-skrip'tās)
Polymerase associated with process of transcription; may be RNA or DNA dependent.
[L. transcribo, pp. transcriptum, to copy, + -ase]

transcriptase

RNA polymerase; an enzyme that catalyzes the synthesis (polymerization) of RNA from ribonucleoside triphosphates, with DNA serving as a template.

reverse transcriptase
RNA-directed DNA polymerase; an enzyme of retroviruses and hepadnaviruses that catalyzes the transcription of RNA to DNA.
viral transcriptase
see reverse transcriptase (above).
References in periodicals archive ?
Inhibition of reverse transcriptase remains the ideal way to combat this type of retrovirus by blocking the viral replication cycle.
WarmStart RTx Reverse Transcriptase enhances NEB's portfolio of enzymes for nucleic acid detection, including Hot Start Taq DNA Polymerase, Q5 Hot Start High Fidelity DNA Polymerase, Bst 2.
nucleoside analogue reverse transcriptase inhibitors (NRTIs), gp120 inhibitors, protease inhibitors, acetylcholinesterase inhibitors.
In a retrospective multicenter study of 201 patients, positive staining for human telomerase reverse transcriptase (hTERT) in the nucleolus was associated with a twofold higher relative risk of dying after curative resection for hepatic colorectal metastases; the increase was statistically significant (J.
In the first 6 months of therapy among patients on a single nucleoside reverse transcriptase inhibitor, high AST and ALT levels were associated with severe hepatotoxicity (odds ratio [OR] of 2.
In another type of test, RNA isolated from exposed cells was converted to cDNA and amplified by QRT-PCR (quantitative real-time reverse transcriptase polymerase chain reaction) to quantify gene expression.
These drugs are other nucleoside reverse transcriptase inhibitors such as lamivudine, and nonnucleoside reverse transcriptase inhibitors such as nevirapine, and protease inhibitors such as indinavir and ritonavir.
Today Vitalea Science announced it had received a National Institute of Allergy and Infectious Disease (NIAID) grant to develop and test assays to quantify intracellular uptake of the active metabolite of a nucleoside reverse transcriptase inhibitor (NRTI) drug that can be applied to children and neonates.
Nucleoside/Nucleotide Reverse Transcriptase Inhibitors plus Non-nucleoside
Merck has signed a deal with Chimerix Inc for CMX157, an investigational oral nucleoside reverse transcriptase inhibitor currently in Phase I clinical development.
The reverse transcriptase protein is the main HIV enzyme responsible for viral replication.
A reverse transcriptase enzyme used in gene expression analysis, PrimeScript can synthesize cDNA in an efficient fashion.

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