Many of these enter saliva from the serum by passing through the spaces between the cells by transcellular
(passive intracellular diffusion and/or active transport) or paracellular (extracellular ultrafiltration) routes.
60] Alternatively, the 'transcellular
tau propagation hypothesis' describes transcellular
tau spreading as a 'prion-like' process.
fluids are also a component of ECF and are found in the cerebrospinal column, pleural cavity, lymph system, joints, glandular secretions, and eyes.
Particularly, absorption of compounds by passive transcellular
diffusion is adequately captured within the Caco-2 cell model with good in vitro-in vivo correlations (Cascone et al.
The lipophilic moiety option may result in membrane penetration or attachment via active or transcellular
passive transport or may simply help to increase protein stability (17).
Bacterial penetration may in principle either be paracellular, via penetration through intercellular tight junctions, or transcellular
, following invasion and/or damage to cells.
pathway is the most direct route that the drug can pass through the skin.
Although lymphocytes were reported to cross the endothelial barrier using both paracellular (between adjacent ECs) and transcellular
(through the cytoplasm of ECs) migration routes, Schoefl clearly showed, using electron microscopic and mathematical analyses, that lymphocytes predominantly use the paracellular route to exit HEVs.
Minireview on regulation of intestinal calcium absorption emphasis on molecular mechanisms of transcellular
pathway Int J Gastroenterol 2008;77:22-34.
DWI measures the random (Brownian) extra-, intra- and transcellular
motion of water molecules.
that the transcellular
water flow is facilitated and regulated by water
Exosomes account for vesicle-mediated transcellular
transport of activatable phospholipases and prostaglandins," Journal of Lipid Research, vol.