For example, active/inactive reference estrogen agonists may be identified from ER binding, ER transactivation
, cell proliferation, or ER cofactor recruitment assays.
Evi-1 raises AP-1 activity and stimulates c-fos promoter transactivation
with dependence on the second zinc finger domain.
Overexpression of ERbeta is sufficient to inhibit hypoxiainducible factor-1 transactivation
In vitro and animal studies indicated that metformin inhibits adipocyte differentiation and stimulates osteoblasts' differentiation, through the inhibition of PPAR gamma  and the transactivation
of osteoblast-specific Runx2 transcription factor .
The Neh4 and Neh5 domains seem to be essential for NRF2 transactivation
and the Neh6 domain is required for NRF2 protein degradation [32, 33].
Porphyromonas gingivalis lipopolysaccharide-induced up regulation in endothelin-1 interferes with salivary mucin synthesis via epidermal growth factor receptor transactivation
8226; Decreases side effects due to transactivation
The present project aims at identifying (i) signals from flagellin-stimulated epithelial cells that are of paramount importance in the transactivation
of dendritic cells, (ii) dendritic cell factors that condition T and B lymphocytes to produce specific mucosal immune responses, and (iii) unique features of memory responses in the mucosa.
Statins prevent NF-kB transactivation
independently of the IKK-pathway in human endothelial cells.
Dissociation of transactivation
from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects.
The N terminal of the A/B domain has a transactivation
function, and the C domain contains two zinc finger motifs, which is formed by a number of cysteine residues and necessary for DNA binding.
Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation