tranexamic acid


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Related to tranexamic acid: Cyklokapron

tranexamic acid

 [tran″ek-sam´ik]
an agent that combats fibrinolysis by competitively inhibiting activation of plasminogen; used in prophylaxis and treatment of hemorrhage associated with excessive fibrinolysis, such as that following oral surgery in patients with hemophilia; administered orally or intravenously.

tran·ex·am·ic ac·id

(tran'eks-am'ik as'id),
A competitive inhibitor of plasminogen activation and of plasmin; used in hemophilia to reduce or prevent hemorrhage.

tranexamic acid

A drug that interferes with the dissolution of blood clot (fibrinolysis) and can be used to prevent bleeding during minor operations such as tooth extraction in people with HAEMOPHILIA. A brand name is Cyklokapron.
References in periodicals archive ?
A meta-analysis of the effectiveness and safety of using tranexamic acid in primary unilateral total knee arthroplasty.
Clinical observation of blood loss reduced by tranexamic acid during and after caesarean section: a multi-center, randomized trial.
Topical intra-articular compared with intravenous tranexamic acid to reduce blood loss in primary total knee replacement a double-blind, randomized, controlled, noninferiority clinical trial .
Caption: Figure 1 Comparisons in intraoperative blood loss parameters among the tranexamic acid (TXA) was found to be more effective at reducing total blood loss compared with epsilon-aminocaproic acid (AM) and the no antifibrinolytic (none) groups.
Topical administration of tranexamic acid in primary total hip and total knee arthroplasty.
Of 2,000 published cases of melasma treated with tranexamic acid to date, "this is the only severe event ever seen with tranexamic acid," he noted.
Suresh et al., "A randomised, open-label, comparative study of tranexamic acid microinjections and tranexamic acid with microneedling in patients with melasma," Journal of Cutaneous and Aesthetic Surgery, vol.
Hurskainen, "Tranexamic acid for the treatment of heavy menstrual bleeding: efficacy and safety," International Journal of Women's Health, vol.
Guillot, "Efficacy of tranexamic acid in sporadic idiopathic bradykinin angioedema," Allergy: European Journal of Allergy and Clinical Immunology, vol.
Three tranexamic acid-carrying modes of emulsified particles--(a) encapsulation, (b) adsorption, and (c) encapsulation plus adsorption--were prepared through the procedures displayed in Table 1; 3 wt.% tranexamic acid ("TA" hereafter) was introduced in the three tranexamic acid-containing emulsions ("[TA.sub.EN]" for encapsulation, "[TA.sub.AD]" for adsorption, and "[TA.sub.EN+AD]" for encapsulation plus adsorption hereafter).
[3] Studies have showed that antifibrinolytic therapy such as tranexamic acid, aminocaproic acid, recombinant factor VII, and platelet transfusions is the beneficial therapies for a patient with GT.