tranexamic acid


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Related to tranexamic acid: Cyklokapron

tranexamic acid

 [tran″ek-sam´ik]
an agent that combats fibrinolysis by competitively inhibiting activation of plasminogen; used in prophylaxis and treatment of hemorrhage associated with excessive fibrinolysis, such as that following oral surgery in patients with hemophilia; administered orally or intravenously.

tran·ex·am·ic ac·id

(tran'eks-am'ik as'id),
A competitive inhibitor of plasminogen activation and of plasmin; used in hemophilia to reduce or prevent hemorrhage.

tranexamic acid

/tran·ex·am·ic ac·id/ (tran″ek-sam´ik) an antifibrinolytic that competitively inhibits activation of plasminogen; used as a hemostatic in the prophylaxis and treatment of severe hemorrhage associated with excessive fibrinolysis.

tranexamic acid

[tran′ek-sam′ik]
an agent that combats fibrinolysis by competitively inhibiting activation of plasminogen. It is used in prophylaxis and treatment of hemorrhage associated with excessive fibrinolysis, such as that after oral surgery in patients with hemophilia. It is administered orally or intravenously.

tranexamic acid

A drug that interferes with the dissolution of blood clot (fibrinolysis) and can be used to prevent bleeding during minor operations such as tooth extraction in people with HAEMOPHILIA. A brand name is Cyklokapron.

tranexamic acid

an antifibrinolytic agent, used orally or intravenously to control hemorrhage. Called also Vasolamin.
References in periodicals archive ?
Group A patients was treated with topical hydroquinone 2% cream applied at night on the affected area and group B was treated with oral tranexamic acid (250mg bid) for 8 weeks.
The instillation of hemostatic factors such as tranexamic acid on the bleeding site is a new technique that has been investigated recently.
The use of intravenous tranexamic acid in patients undergoing total hip or knee arthroplasty: A retrospective analysis at a single military institution.
Tranexamic acid was listed under Group B inside Malaysian regulatory classification.
Intra-articular soaking of tranexamic acid offers an innovative therapeutic approach for decreasing total blood loss and transfusions rate.
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
The data therefore imply that the latter group presents later to medical care and that this delay in seeking care is the greatest factor in their ineligibility for tranexamic acid, rather than the time taken to reach hospital once the emergency services are aware of the incident.
Keywords: Cardiac surgery, Protamine, Tranexamic acid, Post-operative blood loss.
Nasal packing was removed and new pack introduced on day four three hours after removal of nasal packing patient again had second episode of bleeding since admission which was controlled on platelet concentrate administration and tranexamic acid both iv and local application along with anterior and posterior nasal packing.
Ten animals of the second group were treated with a combination of antifibrinolytic drug tranexamic acid (Transamine injection 250mg x 10) and sodium acid pohosphate.
The company's patent combines tranexamic acid with an antibiotic so as to provide the clotting effects along with protection or treatment against infection in a transdermal, local intra-wound application or intra-cavity instillation formulation.