Merkel cell tumor

(redirected from trabecular carcinoma)

Mer·kel cell tu·mor

a rare malignant cutaneous tumor seen in sun-exposed skin of elderly patients composed of dermal nodules of small round cells with scanty cytoplasm in a trabecular pattern; the tumor cells contain cytoplasmic dense core granules resembling neurosecretory granules seen in Merkel cells.
Farlex Partner Medical Dictionary © Farlex 2012


Friedrich Sigmund, German anatomist and physiologist, 1845-1919.
Merkel cell tumor - a rare malignant cutaneous tumor. Synonym(s): primary neuroendocrine carcinoma of the skin; trabecular carcinoma
Merkel corpuscle - a specialized tactile sensory nerve ending in the epidermis. Synonym(s): Merkel tactile cell; Merkel tactile disk; tactile meniscus
Merkel tactile cell - Synonym(s): Merkel corpuscle
Merkel tactile disk - Synonym(s): Merkel corpuscle
Medical Eponyms © Farlex 2012
References in periodicals archive ?
Based on the histologic features, he named the tumor trabecular carcinoma [3].
Rare cases of hyalinising trabecular carcinoma have been reported with recurrence and metastases to lung and lymph nodes.
Toker, "Trabecular carcinoma of the skin," Archives of Dermatology, vol.
Trabecular carcinoma of the skin: An ultrastructural study.
It is a rare, highly malignant primary skin tumour, originally called "trabecular carcinoma" of the skin.
Trabecular carcinoma of the skin: further clinicopathologic and ultrastructural study.
Merkel cell carcinoma, also known as neuroendocrine carcinoma or trabecular carcinoma, is a "very worrisome diagnosis," she said.
Merkel cell carcinoma (MCC) is a rare, highly aggressive cutaneous neuroendocrine neoplasm first described in 1972 by Toker (1) as a variant of sweat gland carcinoma called trabecular carcinoma. According to the data from Surveillance, Epidemiology and End Results, the years 1986 to 2001 have seen a 3-fold increase in MCC cases, (2) with a predicted 1500 cases per year in the United States.
In 1972, Toker first described a trabecular carcinoma of the skin [7].
In 1972, Toker described an unknown, trabecular carcinoma of the skin in five caucasian patients [3].