The 14 chapters grew out of a symposium at the Environmental Mutagenesis and Genomics Society's September 2014 meeting in Orlando, Florida, where many of the chapter authors presented papers on toxicogenomics
and risk assessment.
Permanent links to the National Library of Medicine (NLM) TOXNET records are now provided for the Hazardous Substances Data Bank (HSDB), TOXLINE, LactMed, Developmental and Reproductive Toxicology Database (DART), Toxics Release Inventory (TRI), Comparative Toxicogenomics
Database (CTD), Integrated Risk Information System (IRIS), International Toxicity Estimates for Risk (ITER), Chemical Carcinogenesis Research Information System (CCRIS), and GENE-TOX.
To identify associated dysfunctions and diseases, they integrated protein-disease annotations into the protein complexes using the Online Mendelian Inheritance in Man database and the Comparative Toxicogenomics
Applications of toxicogenomics
in safety evaluation and risk assessment.
Their areas of expertise are toxicogenomics
, pharmacogenomics and oncology.
Topics include: analysis and interpretation of toxicogenomic
data, principles of data mining, study design issues, sources of variability in toxicogenomic
as a tool to assess immunotoxicity, and potential uses of toxicogenomic
biomarkers in occupational health and risk assessment.
and ecotoxicogenomics for studying endocrine disruption and basic biology.
A new report issued today by the National Academies of Sciences (NAS) recognizes the importance of toxicogenomics
in predicting effects on human health and recommends the integration of toxicogenomics
into regulatory decision making.
Collaborative research in various fields of medicine has led to the creation of new disciplines such as pharmacogenomics and toxicogenomics
scientists at Paradigm Genetics are building a database of toxicogenomics
CuraGen scientists will apply the company's Predictive Toxicogenomics
Screen and protein pathway mapping technologies to gain a better understanding of the mechanisms that enable drugs to effectively treat certain diseases.
is the study of the alteration of those mechanisms that leads to conclusions about disease and disease processes.