toxicogenomics


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toxicogenomics

analysing the toxicity of substances by applying the whole genome approach. This field is based on the premise that responses to TOXIC chemicals have their origin in GENE EXPRESSION. Determining how genes respond to toxicants could provide a direct measure of their toxicity. DNA MICROARRAYS/CHIPS are central to this, since they enable the expression of thousands of genes to be monitored simultaneously and a specific gene expression profile to be generated for each toxin.