toxicodynamics

toxicodynamics

(tok″sĭ-kō-dī-nam′iks) [ toxico- + dynamics]
The processes that affect the uptake of, metabolism by, damage to, and disposal of a poison by an organism.

toxicodynamics

the physiological mechanisms by which toxins are absorbed, distributed, metabolized and excreted.
References in periodicals archive ?
At the municipal level, environmental contamination and human poisoning estimates may be inferred according to the type of predominant crop in the municipality, the types of pesticides used and their toxicological characteristics (such as toxicodynamics and toxicokinetics), serving as a warning to health professionals to subsidize Health Surveillance actions.
Cohort 2A was designed as an observational birth cohort of lead toxicodynamics during pregnancy, with mothers recruited early during pregnancy from 1997 to 2001.
3 Data-derived prior distribution for population variability in toxicodynamics (default distribution)
In this regard, the next two sections will be focused on the relevance of genetic polymorphisms in toxicokinetics and toxicodynamics in PD.
Effect of isoproturon pretreatment on the biochemical toxicodynamics of anilofos in male rats.
The modeling topic of ENTOX mainly comprise (a) identification of the pathogen-pollutants and toxic stressor-effect relationship; (b) fate, behavior and transport of organic/non-organic toxic compounds degradation in exposure medium [2-4]; (c) absorption, distribution, metabolism and excretion of environmental contaminants within exposure sentinel species, human and animal [5-7]; (d) toxicokinetics (TK) and toxicodynamics (TD) mechanism at target sites [8]; and (e) risk assessment of toxic pollutant propagation from organisms to populations and variations in ecosystem sensitivities under various scenarios [5,9].
Figure 1 shows a simplified representation of a framework utilizing information from various in vitro and in vivo studies in conjunction with in silico models like the one described in this article, to support better understanding of nanoparticle toxicodynamics.
His topics include unwanted chemical substances, toxicodynamics, naturally inherent plant toxicants, mycotoxins, pesticides and persistent organic pollutants, food additives and flavorings, food allergies and intolerances, and genetically modified organisms.