toxicity


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toxicity

 [tok-sis´ĭ-te]
the quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison.
developmental toxicity the extent to which a toxin produces adverse effects on a developing embryo or fetus; see also teratogenesis.
maternal toxicity a toxic effect on a pregnant woman or nursing mother, as opposed to one affecting an embryo, fetus, or nursing infant.

tox·ic·i·ty

(tok-sis'i-tē),
The state of being poisonous.

toxicity

/tox·ic·i·ty/ (tok-sis´ĭ-te) the quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison.
O2 toxicity , oxygen toxicity serious, sometimes irreversible, damage to the pulmonary capillary endothelium associated with breathing high partial pressures of oxygen for prolonged periods.

toxicity

(tŏk-sĭs′ĭ-tē)
n. pl. toxici·ties
1. The quality or condition of being toxic.
2. The degree to which a substance is toxic.

toxicity

[toksis′itē]
Etymology: Gk, toxikon
1 the degree to which something is poisonous.
2 a condition that results from exposure to a toxin or to toxic amounts of a substance that does not cause adverse effects in smaller amounts.

toxicity

The sum of adverse effects 2º to exposure to a toxic substance, by mouth, through the skin or respiratory tract. See Amalgam toxicity, Botanical toxicity, Developmental toxicity, Digitalis/digoxin toxicity, Diphtheria toxicity, Excitotoxicity, Hashitoxicosis, Immunologic toxicity, Neurotoxicity, Nickel toxicity, Oxygen toxicity, Reproductive toxicity, Vitamin A toxicity.

tox·ic·i·ty

(tok-sis'i-tē)
The state of being poisonous.

toxicity

The quality or degree of poisonousness.

toxicity,

n the poisonous characteristics of a substance.

tox·ic·i·ty

(tok-sis'i-tē)
State of being poisonous.

toxicity (toksis´itē),

n the ability of a drug or poison to produce harm, especially to cause permanent injury or death. Usually distinguished from
allergenic properties.
toxicity, acute,
n a condition produced after short-term use of a toxic agent. See also dose, lethal, median; dose, lethal, minimum.
toxicity, chronic,
n a condition produced after long-term use of a toxic agent.
toxicity, fluoride,
n See fluoride toxicity.
Enlarge picture
Toxic shock syndrome.

toxicity

the characteristic or quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison. See also toxicosis.

toxicity rating
includes slightly toxic (with an oral LD50 in rats of 5000 to 15,000 mg/kg) up to supertoxic (with an LD50 of less than 5 mg/kg).
References in periodicals archive ?
Biomarkers of toxicity offer the hope of producing safer drugs while cutting costs and time to market and are inspiring some novel collaborations.
There are disadvantages, however, to such specific measures of toxicity.
Sample characterization of automobile and forklift diesel exhaust particles and comparative pulmonary toxicity in mice.
This raises the possibility, Fowler says,that it may someday be possible to diagnose the source of a person's toxicity by matching his or her body levels of various porphyrins to a map of ratios that typify exposures to a specific chemical or mix of chemicals.
A description of the response additivity model is available on our website [Computational Approach to the Toxicity Assessment of Mixtures (CATAM) 2006a] along with a mixtures toxicity calculator used in these analyses (CATAM 2006b).
Going forward, SNBL plans to proceed with research and aims to develop an innovative tool for toxicity analysis of drug candidates.
MULTIPLE PERSONALITIES A variety of factors need to be considered to evaluate the toxicity of engineered nanoparticles.
Amiodarone pulmonary toxicity (APT) is usually manifested by acute pneumonitis and chronic fibrosis.
Both men and women (but especially women) with a high CD4 count are at greater risk of liver toxicity from nevirapine than those with more advanced HIV disease.
Rutka: Some evidence indicates that there might be a simple way to prevent aminoglycoside toxicity, especially from the basic science research concerning the prevention of oxygen and nitrogen radical species.
The good news is that there are noninvasive ways to remove residual metal toxicity in your body, as well as countless other toxins.
The study concluded that a dose of KOS-862 100mg/m2 given weekly three out of four weeks was well tolerated and was associated with only mild to moderate toxicity.