toxic multinodular goiter
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enlargement of the thyroid gland, causing a swelling in the front part of the neck; called also struma. adj., adj goit´rous. If there is evidence of pressure against the throat, or the possibility of a malignancy, the goiter may be removed surgically. Simple endemic goiter is usually caused by lack of iodine in the diet. In graves' disease, goiter is accompanied by excessive thyroid hormones in the blood and symptoms of hyperthyroidism.
aberrant goiter goiter of a supernumerary thyroid gland.
adenomatous goiter that caused by adenoma or multiple colloid nodules of the thyroid gland.
Basedow goiter a colloid goiter that has become hyperfunctioning after administration of iodine.
colloid goiter one that is large and soft and has distended spaces filled with colloid.
cystic goiter one with cysts formed by mucoid or colloid degeneration.
diffuse toxic goiter exophthalmic goiter.
endemic goiter goiter occurring widely in a geographic region where the food or water is deficient in iodine. Treatment consists of iodine replacement; although this will not cure the condition, it can stop it from enlarging, and iodine administered in advance will prevent development of goiter.
exophthalmic goiter any type accompanied by exophthalmos.
fibrous goiter goiter in which the thyroid capsule and stroma are hyperplastic.
follicular goiter parenchymatous goiter.
intrathoracic goiter one with part of the enlarged gland in the thoracic cavity.
iodide goiter that occurring in reaction to iodides at high concentrations, due to inhibition of iodide organification.
multinodular goiter one with circumscribed nodules within the gland.
nontoxic goiter that occurring sporadically and not associated with hyperthyroidism or hypothyroidism.
parenchymatous goiter one with increase in follicles and proliferation of epithelium.
perivascular goiter one that surrounds a large blood vessel.
retrovascular goiter one with processes behind a large blood vessel.
substernal goiter one whose lower part lies beneath the sternum.
suffocative goiter one that causes dyspnea due to pressure.
toxic multinodular goiter hyperthyroidism arising in a multinodular goiter, usually of long standing.
vascular goiter one due chiefly to dilatation of the blood vessels of the thyroid gland.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
toxic multinodular goiterEndocrinology A hyperthyroid state characterized by innumerable functionally active nodules producing excess thyroid hormone Clinical Hyperthyroidism without ophthalmoplegia Risk groups ♀ > age 60. See Goiter.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.