toxic hepatitis


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Related to toxic hepatitis: Liver toxicity

toxic hepatitis

hepatitis produced by a hepatotoxin, such as Amanita phalloides toxin; carbon tetrachloride; or any of various drugs.

toxic hepatitis

Inflammation of the liver caused by the ingestion or absorption of toxins or drugs into the body. Included in the great number of agents known to be able to cause this type of hepatitis are common drugs and chemicals (such as halothane, isoniazid, anabolic steroids, carbon tetrachloride, trichlorethylene) used in either the treatment of disease or in the workplace.
See also: hepatitis
References in periodicals archive ?
The fact that the animal has been previously examinated by a veterinary and laboratorial parameters before the administration of PGF2[alpha] suggests that this substance was the cause of acute toxic hepatitis and it was not necessary nor indicated to expose the animal to the risk of another test administration of the drug.
In the present case, ALT was increased more than ten times, indicating severe hepatic damage, compatible to acute toxic hepatitis.
In this patient, though, as the cause of the seizures presented by the animal was not known, diazepam was used and this may have induced the coma state in the animal with acute toxic hepatitis.
KEY WORDS: complex exposure, dimethylacetamide, hepatotoxicity, industrial waste, liver biopsy, toxic hepatitis.
These findings were compatible with the remission stage of acute hepatitis and also with toxic hepatitis.
In a case report of toxic hepatitis caused by this herb component, Hwang et al.
We suspect that the unslaked lime process is responsible for the development of this toxic hepatitis outbreak for the following reasons: a) during the 2 years before the outbreak, there were no significant changes in the amount and composition of the wastes or in the origin of the raw waste materials, except for the introduction of this unslaked lime process; b) no cases of hepatitis occurred before the introduction of the unslaked lime process; and c) simulation of the unslaked lime process showed that several hepatotoxic materials are generated in the waste and vapors.
DMAc and DMF, both solvents that can potentially cause acute toxic hepatitis (Baum and Suruda 1997; Choi et al.
1988) suspected that toxic hepatitis could be caused by the synergistic interaction of various unknown chemicals generated during the unslaked lime process through thermochemical reactions.
We conclude that this outbreak of toxic hepatitis developed as a result of exposure to the hepatotoxic materials generated during the treatment of industrial waste using unslaked lime.