toxic coreA hypothetical substrate which increases cardiovascular mortality in type-A individuals, who are typically angry, cynical, distrustful and repress marked hostility towards others. Clinical data suggest that long-term cardiovascular mortality is up to seven-fold greater in subjects with a “toxic core” personality.
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toxic corePsychiatry A 'factor' hypothesized to ↑ cardiovascular mortality–CM in type As, who are angry, cynical, distrustful, and repress marked hostility towards others. See Negative emotions, Toxic emotion, Type A personality.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.