total lymphocyte count


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total lymphocyte count

Abbreviation: TLC
The number of lymphocytes in a specimen of blood. The count may be increased in clonal diseases such as chronic lymphocytic leukemia or decreased in diseases such as AIDS. In AIDS, decreases in the total lymphocyte count usually reflect a marked decline in the number of helper T4 cells.
See also: count
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A recent study comparing the cost-effectiveness of CD4 counting to total lymphocyte count testing (TLC) and viral load (VL) testing found that in the absence of second line ARV, CD4 tests are a more cost effective laboratory testing strategy for managing HIV infection.

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