total PSA

total PSA

A “raw” PSA serum level (4-10 ng/mL) (as well as a normal digital rectal examination) on which a  doctor will base his or her decision to refer a patient for a prostate biopsy. There is a 20-30% cancer detection rate at a PSA of 4-10 ng/mL.
References in periodicals archive ?
Peer-reviewed published studies support the use of the phi test in men with total PSA values as low as 2 ng.
The combination of free PSA and total PSA was approved for cancer detection by the FDA in 1998 and is useful in cases with moderately elevated total PSA (4.
Of 14,916 men from the randomized, controlled Physicians' Health Study who submitted a blood specimen prior to enrollment, 234 with total PSA levels available prior to age 60 years had prostate cancer diagnosed between 1983 and 1993, and 711 served as age-matched controls.
Measurement of the ratio of free to total PSA may increase the specificity of PSA testing.
In their study with men between the ages of 40 and 69, Gray and colleagues reported significantly lower free PSA (fPSA) and fPSA% values in smokers than in non-smokers, but total PSA (tPSA) did not show such a difference.
Compared with plain wheat bread (which is low in anticancer phytoestrogens), total PSA went down 12.
Medicare in Australia will not reimburse claims for a free PSA if the total PSA result is not accompanied by the age-related normal range.
In other words, if a man"s PSA has risen rapidly in recent years, there is no cause for concern if his total PSA level is still low and his clinical exam is normal," he added.
Serum total PSA decreased or was unchanged in 69% of the subjects in the isoflavone treated group compared to 55% in the placebo group.

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