Multiple clinical trials have investigated the use of a variety of pharmacologic agents and nonpharmacologic supplements, such as 5-[alpha] reductase inhibitors, 3,3'-diindolylmethane, selenium, soy compounds, toremifene
citrate, green tea catechins, and lycopenes, among others, but none of these agents has emerged as particularly promising for effective chemoprevention of prostate cancer (as reviewed in DeMarzo et al (3)), although some trials are still ongoing to date.
Compartmentalized uterotrophic effects of tamoxifen, toremifene
, and estradiol in the ovariectomized Wistar (Han) rat.
In a new research, scientists said the painkiller ibuprofen and the chemotherapy drug toremifene
can "disable" the Ebola virus.
Effect of combined therapy with the antiestrogen agent toremifene
and local hyperthermia on breast cancer cells implanted in nude mice.
Glucose-6-phosphate (G6P), glucose-6-phosphate dehydrogenase (G6PDH), and pnicotinamide adenine dinucleotide phosphate (NADP+), tamoxifen (TAM), 4'-hydroxytamoxifen (HTAM), toremifene
(TOR), 4'-hydroxytoremifene (HTOR), and mebendazole (MBZ, internal standard, IS) were obtained from Sigma-Aldrich (St.
Comparing the effects of atamestane, toremifene
and tamoxifen alone and in combination, on bone, serum lipids and uterus in ovariectomized rats.
002 ([section]) Virus variant Toremifene
or subtype [EC.
I generation: Tripbenylethylene derivative- Tamoxifene, Droloxifene, Toremifene
Interferons could also be possible candidates, Friede said, adding that the experts had also discussed breast cancer drug toremifene
, but found significant "safety concerns.
to reduce fracture risk in men receiving androgen deprivation therapy for prostate cancer.
Relevance of the selective oestrogen receptor modulators tamoxifen, toremifene
and domiphene in doping field: endogenous steroids urinary profile after multiple oral doses.
The findings open the way for further testing of the drugs, clomiphene and toremifene
, against the deadly virus.