Doctors have prescribed a two-month course of Topotecan
, which is still being tested in the UK and is used by sufferers who do not respond to more conventional treatments.
Meanwhile, Jade will start a two-month course of the new wonder drug Topotecan
, normally administered alongside a course of chemotherapy - a gruelling treatment that has already left Jade's body sick and weak.
She is also being given a new drug Topotecan
, which is still being tested in the UK.
She will begin a two-month course of Topotecan
next week, which it is hoped will shrink the deadly tumours.
During the time period of April 14-18, 1999, intravenous topotecan
was administered to Maura daily for a total of 5 doses, which she received as an outpatient.
Examples of topoisomerase I inhibitors are ironotecan and topotecan
. Topoisomerase II inhibitors are Amsacrine and Etoposide.
Various drugs which has been used as a radio sensitizer for concurrent chemo radiation include hydroxyurea (4), mitomycin-C (5) 5-fluorouracil, Irinotecon, Topotecan
, and Paclitaxel in combination with cisplatin (6-9).
Researchers reported at the SGO meeting that adding thalidomide to the chemotherapy drug topotecan
improved disease-free survival in recurrent ovarian cancer (as well as in primary peritoneal or fallopian tube cancers).
(Hycamtin): This drug is used to treat metastatic (cancer that has spread) ovarian cancer after initial or subsequent chemotherapy has failed.
A recent clinical trial, conducted by the Gynecologic Oncology Group, has demonstrated that the combination of cisplatin and topotecan
is the current standard combination for the management of metastatic disease requiring chemotherapy.