topical microbicide


Also found in: Dictionary, Encyclopedia.

topical microbicide

Infectious disease A chemical that can be applied to the surface of the body to kill microorganisms
References in periodicals archive ?
Moreover, because they are rarely immunogenic, aptamers are ideally suited for therapeutic applications like topical microbicides, which may require repeated administration.
Studies of topical microbicides have increasingly overlapped with studies of the use of systemic chemoprophylaxis (i.e., pre- or postexposure prophylaxis) to prevent HIV transmission (see below).
Biomedical engineers have developed a computer tool they say could lead to improvements in topical microbicides being developed for women to use to prevent infection by the virus that causes AIDS, report researchers at Duke University, Durham, N.C.
The second section focuses on types of diseases, risk factors, symptoms, and treatment, followed by testing and diagnosis; prevention and safe sex; discussing STDs with partners, health care professionals, and children; and recent research on vaccines, topical microbicides, and clinical trials for people with HIV/AIDS.
Developing topical microbicides (preparations that can be inserted into the vagina to prevent infection) that are effective and easy for women to use is also a major research focus.
The future may also give us topical microbicides and HIV vaccines, which may not provide complete protection but can enhance our HIV prevention arsenal.
What are the best candidates for development as topical microbicides? Bridges noted that research in this area is still in its infancy.
The limited control females have over condom use has led to interest in methods that could be female controlled, such as the female condom or topical microbicides (Coggins, 1999; Darroch & Frost, 19 99; El-Bassel, Krisbnam, Schilling, Witte, & Gilbert, 1998; Gollub, Stein, & El-Sadr, 1995; Rosenthal, Biro, & Stanberry, 1998).
Advances in topical microbicides. Presented at the XIII International AIDS Conference, July 9-14, 2000, Durban, South Africa.
(22.) Heise L, Topical Microbicides: New Hope for STI/HIV Prevention, Takoma Park, MD: Center for Health and Gender Equity, n.d., p.
Topical microbicides are vaginally or rectally administered agents designed to block HIV attachment to or insertion in susceptible target cells, and research to find a safe and effective microbicide has been going on for about a decade already.
Topical microbicides, substances that are applied in either the vagina or the rectum to reduce the risk of infection, currently hold great promise, in part because they do not require the active participation or even knowledge of the partner.