tophi


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to·phi

(tō'fī),
Plural of tophus.

tophus

[tō′fəs] pl. tophi
Etymology: L, tufa, porous rock
a calculus containing sodium urate that develops in fibrous tissue around joints, typically in patients with gout. -tophaceous, adj.
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Tophus

to·phi

(tō'fī)
Plural of tophus.
Enlarge picture
TOPHI: Left and right hands of a patient with multiple deforming gouty tophi
Enlarge picture
TOPHI: Left and right hands of a patient with multiple deforming gouty tophi

tophus

(to'fus) plural.tophi [L., porous stone]
A deposit of sodium biurate in tissues near a joint, in the ear, or elsewhere in individuals with gout.
Synonym: gouty pearl See: illustration

tophi

Crystals of monosodium urate that may appear as chalky outcroppings on the skin of the ear, or may occur in tendons or joints in GOUT.

Tophus (plural, tophi)

A chalky deposit of a uric acid compound found in gout. Tophi occur most frequently around joints and in the external ear.
Mentioned in: Gout
References in periodicals archive ?
In patients with severe gout (such as tophi, chronic arthritis, and frequent attacks), the serum urate level should be controlled more strictly with a target value <300 [micro]mol/L but lowering the level to <180 [micro]mol/L is not recommended.
Yu and colleagues (3) described a series of seven patients with limited knee ROM secondary to gouty tophi.
At baseline, patients with clinically apparent tophi had more tender and swollen joints, greater disability, and greater arthritis severity, but otherwise their clinical presentation was similar to patients without clinically apparent tophi.
For now, providers should know that "patients with gout are not well served if their serum urate levels remain elevated, as that means they are at ongoing risk for flares and tophi," Dr.
Magnetic resonance imaging (MRI) of the left elbow joint revealed tophi compressing the ulnar nerve (Figure).
These criteria increase their specificity but make them less useful in diagnosing a first episode of gout, when tophi are unlikely to have developed.
Our experience indicates that DECT may be a good choice for the diagnosis of CTS associated with gouty tophi.
When one includes podagra and the presence of tophi, the specificity increases.
Antonie van Leeuwenhoek, best known for his work on the improvement of the microscope, depicted in 1679 the crystals in the gouty tophi, although their chemical composition was not yet known at that moment.
Frequent recurrently attacks of acute gout with the presence of tophi or signs of gouty arthritis may call for long term treatment.
Gout presents as arthropathy, tenosynovitis, bursitis, and cellulitis of noninfectious origin, urinary tract calculi, and very commonly as soft-tissue deposits known as tophi.
Diffuse calcinosis and intradermal tophi in a uremic pateint: effect of low-calcium hemodialysis and mechanism of hypercalcemia.