tophaceous gout


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Related to tophaceous gout: colchicine

to·pha·ceous gout

gout in which deposits of uric acid and urates occur as gouty tophi adjacent to the affected joint.

tophaceous gout

Etymology: L, tufa, porous rock
a form of purine metabolism disorder characterized by formation of chalky deposits of sodium biurate under the skin and in the joints. If untreated, the deposits may eventually destroy the involved joints.

to·pha·ceous gout

(tō-fā'shŭs gowt)
The condition in which deposits of uric acid and urates occur as gouty tophi.

tophaceous gout

Gout marked by the development of tophi (deposits of sodium urate) in the joints and in the external ear.
See also: gout
References in periodicals archive ?
A survey of indications, results and complications of surgery for tophaceous gout.
In conclusion, tophaceous gout should be considered in synovial calcium deposits with atypical localization which are encountered in premenopausal young women without a history of hyperuricemia and acute inflammatory arthritis attacks.
Sudden hypotonic paraparesis caused by tophaceous gout of the lumbar spine.
With the combination of SVP and pegsiticase, we believe we can dramatically improve treatment for patients with refractory and tophaceous gout," said Werner Cautreels, PhD, President and Chief Executive Officer of Selecta.
Chronic tophaceous gout often affects the interphalangeal joints of the hand, mostly asymmetrically, showing central, marginal or periarticular erosions with overhanging edges.
I think the investigators were not as selective as they could have been in patient selection, which is unfortunate because this to me would be an exciting alternative for patients with severe tophaceous gout.
It is a heterogeneous disorder, comprising four phases: asymptomatic hyperuricemia, acute gouty inflammation of joints or bursae, intercritical gout, and chronic tophaceous gout.
Successful treatment with rasburicase of a tophaceous gout in a patient allergic to allopurinol.
First approved therapy in the European Union to address a significant unmet medical need for patients with chronic tophaceous gout
In cases of severe debilitating chronic tophaceous gout, these symptoms have a major influence on patient health-related quality of life due to the frequency and severity of episodes and the recurrent pain, and can also lead to disfigurement associated with this condition.
As a result, numbers of patients with more clinically complex cases of tophaceous gout are increasing.