tooth agenesis, selective, type 1(redirected from tooth agenesis, selective, with orofacial cleft)
tooth agenesis, selective, type 1A condition (OMIM:106600) characterised by non-syndromic agenesis of one or more teeth, which is divided into hypodontia (agenesis of less than 6 permanent teeth) and oligodontia (agenesis of 6 or more permanent teeth).
Caused by defects of MSX1, which encodes a homeobox protein involved in epithelial-mesenchymal signalling that has roles in craniofacial development.
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