This degeneration implies that the normal 35-mm cochlear tonotopic
map , representing the functional length of the normal OC, does not apply to most patients receiving a CI.
Salicylate-induced peripheral auditory changes and tonotopic
reorganization of auditory cortex.
In the tonotopic
organization of sound perception , the cochlea basal section encodes for high frequency stimuli, above 3 kHz.
To address the issue how V1 responsiveness is influenced by auditory stimulation at the systemic level, we recently developed a novel method to simultaneously record a visuotopic map in V1 and a tonotopic
map in A1 in mice using Fourier-based intrinsic signal imaging  (Figure 1).
Utilizing the tonotopic
organization of the auditory system, acoustic CR therapy uses sequences of acoustic tonal stimuli, namely, four different frequencies centered around the characteristic frequency of the patient's tinnitus percept, delivered in nonsimultaneous sequences several hours per day for several weeks .
Theoretically, this strategy generates up to 120 tonotopic
positions, although psychophysical data reveal that most CI users are unable to discriminate such small differences in place pitch [4-7].
Along the auditory pathway, the frequency of the incoming signal is then expressed in a tonotopic
organization, and amplitude is coded by varying the discharge rate of action potentials, while the interval between signals and the duration is coded by different temporal patterns of action potentials.
In cochlear implants, the various electrodes are implanted at various tonotopic
locations in the inner ear.
There have been studies that showed a certain level of intramodal plasticity in the auditory cortex, particularly in the tonotopic
area of the primary auditory cortex (A1).
Some in vivo studies have explored the nucleus ovoidalis for the tonotopic
organization and responsiveness of its neurons to different acoustic stimuli.
Third, the increase in response amplitude at 3 kHz during cold pressor may be related to the tonotopic
nature of the basilar membrane within the cochlea.