The aqueous extract at doses of 1600 and 3200 mg/kg significantly protected 42.86 and 71.43% of the mice from tonic seizure
(P < 0.001) (table 1).
In particular, methanol and aqueous extracts were effective against tonic seizure
, but methanol extract was more active in generalized seizure or myoclonus; these results suggest more concentrated presence of flavonoids such as quercetin implicate major anticonvulsant response.
Other varieties seen were complex partial seizures with or without automatisms, generalised tonic seizures
and complex partial seizures with secondary generalisation.
were classified when neonates showed sustained flexion and extension of extremities and myoclonic seizures were classified when neonates showed lightning fast jerky movements of upper or lower limbs.
Focal clonic and generalized tonic seizures
were identified as significant risk factors for the development of epilepsy [OR values, 5.918, 95% CI (1.241-28.221), p=0.026 and 11.8, 95% CI (1.466-95.526), p=0.02].
The late forms of chronic seizures can appear as tonic seizures
, myoclonic jerks, infantile spasms, multifocal epileptiform activity, or hypsarrhythmia on EEG.
Overall, 80% of children will develop tonic seizures
, 65% atonic seizures, 60% atypical absences and 55% tonic-clonic seizures (7).
It is followed by, an intermediate stage with infantile spasms, and a late stage with multifocal, myoclonic, and tonic seizures
.6 The management involves copper histidine supplementation.7 Hence it is extremely important to identify and report as many cases of this disease as possible.
In this paper we report a patient experiencing complex partial seizures and tonic seizures
secondary to hypothalamic hamartoma displacing mammillary body.
are characterized by stiffening of the muscles.
Her history revealed malaise, loss of appetite, and recurrent afebrile generalized tonic seizures
lasting for 8-10 min in the past month.
Similarly patients with generalized epilepsies such as JME exhibited bilateral asymmetric tonic seizures
or those with JAE exhibited automotor seizures and vice versa.